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sdhC succinate:quinone oxidoreductase, membrane protein SdhC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945316, updated on 23-Apr-2026
Official Symbol
sdhC
Official Full Name
succinate:quinone oxidoreductase, membrane protein SdhC
Primary source
ECOCYC:EG10933
Locus tag
b0721
See related
ASAP:ABE-0002460
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
cybA; cybL; dhsC; ECK0710
Summary
The sdhABCD operon is negatively regulated by ryhB RNA as part of indirect positive regulation by Fur. [More information is available at EcoGene: EG10933]. One of two membrane proteins in the four subunit enzyme. [More information is available at EcoCyc: EG10933].
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Sequence:
NC_000913.3 (755177..755566)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene citrate synthase Neighboring gene protein YbgV Neighboring gene protein YbgU Neighboring gene succinate:quinone oxidoreductase, membrane protein SdhD Neighboring gene succinate:quinone oxidoreductase, FAD binding protein Neighboring gene succinate:quinone oxidoreductase,

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Chromosomal location of the Escherichia coli cytochrome b556 gene, cybA. Murakami H, et al. Mol Gen Genet, 1984. PMID 6237244
  2. Glucose repression of the Escherichia coli sdhCDAB operon, revisited: regulation by the CRP*cAMP complex. Nam TW, et al. Nucleic Acids Res, 2005. PMID 16314304, Free PMC Article
  3. Voltammetric studies of bidirectional catalytic electron transport in Escherichia coli succinate dehydrogenase: comparison with the enzyme from beef heart mitochondria. Pershad HR, et al. Biochim Biophys Acta, 1999 Aug 4. PMID 10482788
  4. Retention of heme in axial ligand mutants of succinate-ubiquinone xxidoreductase (complex II) from Escherichia coli. Maklashina E, et al. J Biol Chem, 2001 Jun 1. PMID 11259408
  5. The quinone-binding site in succinate-ubiquinone reductase from Escherichia coli. Quinone-binding domain and amino acid residues involved in quinone binding. Yang X, et al. J Biol Chem, 1998 Nov 27. PMID 9822661

See all (71) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables electron transfer activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables electron transfer activity IEA
Inferred from Electronic Annotation
more info
  
enables heme binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables succinate dehydrogenase (quinone) activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables ubiquinone binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in aerobic electron transport chain NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within aerobic respiration IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within cytochrome complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
succinate:quinone oxidoreductase, membrane protein SdhC
NP_415249.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    755177..755566
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415249.1 succinate:quinone oxidoreductase, membrane protein SdhC

    See identical proteins and their annotated locations for NP_415249.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1Y2Y5Q8, A0A826KU25, A0A8S7CD19, A0A979GVW8, A0A9P2MM69, A0AA35F804
    Conserved Domains (1) summary
    PRK09487
    Location:1 → 129
    sdhC; succinate dehydrogenase cytochrome b556 subunit
Nucleotide Protein
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