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araD L-ribulose-5-phosphate 4-epimerase AraD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945294, updated on 3-Dec-2024

Summary

Official Symbol
araD
Official Full Name
L-ribulose-5-phosphate 4-epimerase AraD
Primary source
ECOCYC:EG10055
Locus tag
b0061
See related
ASAP:ABE-0000209
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0062
Summary
AraD is a masked class II aldolase. [More information is available at EcoGene: EG10055]. L-ribulose 5-phosphate 4-epimerase catalyzes the third step in the pathway for degradation of L-arabinose, the epimerization at the C4 carbon to form D-xylulose-5-phosphate, which enters the |FRAME: [More information is available at EcoCyc: EG10055].
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Genomic context

Sequence:
NC_000913.3 (65855..66550, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNA polymerase-binding ATPase and RNAP recycling factor Neighboring gene DNA polymerase II Neighboring gene L-arabinose isomerase Neighboring gene ribulokinase

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-ribulose-phosphate 4-epimerase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables L-ribulose-phosphate 4-epimerase activity IEA
Inferred from Electronic Annotation
more info
 
enables aldehyde-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
L-ribulose-5-phosphate 4-epimerase AraD
NP_414603.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    65855..66550 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414603.1 L-ribulose-5-phosphate 4-epimerase AraD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414603.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6N8NFH2
    Conserved Domains (1) summary
    PRK08193
    Location:1231
    araD; L-ribulose-5-phosphate 4-epimerase AraD