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gltL glutamate/aspartate ABC transporter ATP binding subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945254, updated on 19-Nov-2025
Official Symbol
gltL
Official Full Name
glutamate/aspartate ABC transporter ATP binding subunit
Primary source
ECOCYC:EG12663
Locus tag
b0652
See related
ASAP:ABE-0002232
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0645
Summary
GltL is the ATP binding component of the glutamate ABC transporter. [More information is available at EcoCyc: EG12663].
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Sequence:
NC_000913.3 (684530..685255, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene chaperone protein HscC Neighboring gene pyrimidine-specific ribonucleoside hydrolase RihA Neighboring gene glutamate/aspartate ABC transporter membrane subunit GltK Neighboring gene glutamate/aspartate ABC transporter membrane subunit GltJ Neighboring gene ncRNA Neighboring gene glutamate/aspartate ABC transporter periplasmic binding protein

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Interactions of a glutamate-aspartate binding protein with the glutamate transport system of Escherichia coli. Willis RC, et al. J Biol Chem, 1975 Apr 10. PMID 1091636
  2. Purification and properties of a periplasmic glutamate-aspartate binding protein from Escherichia coli K12 strain W3092. Willis RC, et al. J Biol Chem, 1975 Apr 10. PMID 1091635
  3. Purification and properties of glutamate binding protein from the periplasmic space of Escherichia coli K-12. Barash H, et al. Biochim Biophys Acta, 1975 Mar 28. PMID 236016
  4. Effect of growth conditions on glutamate transport in the wild-type strain and glutamate-utilizing mutants of Escherichia coli. Kahane S, et al. J Bacteriol, 1976 Mar. PMID 767325, Free PMC Article
  5. Bacterial evolution through the selective loss of beneficial Genes. Trade-offs in expression involving two loci. Zinser ER, et al. Genetics, 2003 Aug. PMID 12930738, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ABC-type amino acid transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled L-glutamate tranmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled polar amino acid-transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-aspartate import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in L-glutamate import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
glutamate/aspartate ABC transporter ATP binding subunit
NP_415185.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    684530..685255 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415185.1 glutamate/aspartate ABC transporter ATP binding subunit

    See identical proteins and their annotated locations for NP_415185.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6C9QH93
    Conserved Domains (1) summary
    COG1126
    Location:1 → 240
    GlnQ; ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]
Nucleotide Protein
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