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fepD ferric enterobactin ABC transporter membrane subunit FebD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945214, updated on 4-Feb-2026
Official Symbol
fepD
Official Full Name
ferric enterobactin ABC transporter membrane subunit FebD
Primary source
ECOCYC:EG10296
Locus tag
b0590
See related
ASAP:ABE-0002031
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0583
Summary
FepBCDG are components of a ferric enterobactin transport complex that is a member of the ATP-binding cassette (ABC) family of transporters. [More information is available at EcoCyc: EG10296].
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Sequence:
NC_000913.3 (621185..622189, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene enterobactin biosynthesis protein YbdZ Neighboring gene apo-serine activating enzyme Neighboring gene polysaccharide co-polymerase family protein FepE Neighboring gene ferric enterobactin ABC transporter ATP binding subunit Neighboring gene ferric enterobactin ABC transporter membrane subunit FepG Neighboring gene enterobactin exporter EntS Neighboring gene ferric enterobactin ABC transporter periplasmic binding protein

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Regulatory architecture of the iron-regulated fepD-ybdA bidirectional promoter region in Escherichia coli. Christoffersen CA, et al. J Bacteriol, 2001 Mar. PMID 11222606, Free PMC Article
  2. Escherichia coli periplasmic protein FepB binds ferrienterobactin. Stephens DL, et al. Microbiology (Reading), 1995 Jul. PMID 7551033
  3. Binding of ferric enterobactin by the Escherichia coli periplasmic protein FepB. Sprencel C, et al. J Bacteriol, 2000 Oct. PMID 10986237, Free PMC Article
  4. Fur-DNA interactions at the bidirectional fepDGC-entS promoter region in Escherichia coli. Lavrrar JL, et al. J Mol Biol, 2002 Oct 4. PMID 12367523
  5. Mutations in the Escherichia coli receptor FepA reveal residues involved in ligand binding and transport. Barnard TJ, et al. Mol Microbiol, 2001 Aug. PMID 11532122

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ferric-enterobactin transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ferric-enterobactin import into cell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in iron import into cell NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in siderophore-iron import into cell IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Preferred Names
ferric enterobactin ABC transporter membrane subunit FebD
NP_415122.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    621185..622189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415122.1 ferric enterobactin ABC transporter membrane subunit FebD

    See identical proteins and their annotated locations for NP_415122.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X3JKL0
    Conserved Domains (1) summary
    PRK10441
    Location:1 → 334
    PRK10441; Fe(3+)-siderophore ABC transporter permease
Nucleotide Protein
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