U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mepH peptidoglycan endopeptidase/peptidoglycan L,D-carboxypeptidase MepH [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945210, updated on 30-Jul-2025
Official Symbol
mepH
Official Full Name
peptidoglycan endopeptidase/peptidoglycan L,D-carboxypeptidase MepH
Primary source
ECOCYC:G6892
Locus tag
b1655
See related
ASAP:ABE-0005533
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1651; ydhO
Summary
spr, nlpC, yafL and ydhO are paralogs. [More information is available at EcoGene: EG13949].
NEW
Try the new Gene table
Try the new Transcript table
Sequence:
NC_000913.3 (1734435..1735250)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ATP-dependent helicase Lhr Neighboring gene glutaredoxin 4 Neighboring gene superoxide dismutase (Fe) Neighboring gene putative transporter YdhP

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Three redundant murein endopeptidases catalyse an essential cleavage step in peptidoglycan synthesis of Escherichia coli K12. Singh SK, et al. Mol Microbiol, 2012 Dec. PMID 23062283
  2. MEROPS: the peptidase database. Rawlings ND, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381862, Free PMC Article
  3. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article
  4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
  5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables endopeptidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in capsule polysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
  
involved_in peptidoglycan metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within peptidoglycan metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
peptidoglycan endopeptidase/peptidoglycan L,D-carboxypeptidase MepH

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1734435..1735250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416172.1 peptidoglycan endopeptidase/peptidoglycan L,D-carboxypeptidase MepH

    See identical proteins and their annotated locations for NP_416172.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2H4TZR7
    Conserved Domains (1) summary
    COG0791
    Location:138 → 262
    Spr; Cell wall-associated hydrolase, NlpC family [Cell wall/membrane/envelope biogenesis]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.