U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

rplT 50S ribosomal subunit protein L20 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945152, updated on 19-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
rplT
Official Full Name
50S ribosomal subunit protein L20
Primary source
ECOCYC:EG10881
Locus tag
b1716
See related
ASAP:ABE-0005729
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1714; pdzA
Summary
The L20 protein is a component of the 50S subunit of the ribosome and autoregulates its own expression and that of L35 at the posttranscriptional level. [More information is available at EcoCyc: EG10881].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (1799393..1799749, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene phenylalanine--tRNA ligase subunit alpha Neighboring gene pheST-ihfA operon leader peptide Neighboring gene 50S ribosomal subunit protein L35 Neighboring gene translation initiation factor IF-3

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites. Allemand F, et al. Nucleic Acids Res, 2007. PMID 17439971, Free PMC Article
  2. Coexistence of two protein folding states in the crystal structure of ribosomal protein L20. Timsit Y, et al. EMBO Rep, 2006 Oct. PMID 16977336, Free PMC Article
  3. Double molecular mimicry in Escherichia coli: binding of ribosomal protein L20 to its two sites in mRNA is similar to its binding to 23S rRNA. Guillier M, et al. Mol Microbiol, 2005 Jun. PMID 15916597
  4. The N-terminal extension of Escherichia coli ribosomal protein L20 is important for ribosome assembly, but dispensable for translational feedback control. Guillier M, et al. RNA, 2005 May. PMID 15840820, Free PMC Article
  5. How bacterial ribosomal protein L20 assembles with 23 S ribosomal RNA and its own messenger RNA. Raibaud S, et al. J Biol Chem, 2003 Sep 19. PMID 12840018

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: A method for the chemical generation of N-terminal peptide sequence tags for rapid protein identification.
  2. Only one molecule of L20 protein binds to the L20 mRNA despite the presence of two potential binding sites.
    Title: Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites.
  3. findings demonstrate double molecular mimicry: binding of ribosomal protein L20 to its two sites in mRNA is similar to its binding to 23S rRNA
    Title: Double molecular mimicry in Escherichia coli: binding of ribosomal protein L20 to its two sites in mRNA is similar to its binding to 23S rRNA.
  4. N-terminal tail of L20 is important for ribosome assembly in vivo
    Title: The N-terminal extension of Escherichia coli ribosomal protein L20 is important for ribosome assembly, but dispensable for translational feedback control.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables large ribosomal subunit rRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables mRNA regulatory element binding translation repressor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in negative regulation of translation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within ribosomal large subunit assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in ribosomal large subunit assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within ribosomal large subunit assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
50S ribosomal subunit protein L20

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1799393..1799749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416231.1 50S ribosomal subunit protein L20 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416231.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    W1X3C7
    Conserved Domains (1) summary
    PRK05185
    Location:2 → 115
    rplT; 50S ribosomal protein L20; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.