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tus DNA replication terminus site-binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945135, updated on 10-Oct-2019

Summary

Gene symbol
tus
Gene description
DNA replication terminus site-binding protein
Primary source
EcoGene:EG11038
Locus tag
b1610
See related
ASAP:ABE-0005378; ECOCYC:EG11038
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1605; tau
Summary
Site-specific DNA binding protein Tus arrests the DnaB helicase at six chromosomal Ter sites (A-F), blocking replication forks. [More information is available at EcoGene: EG11038]. Tus, also known as ter-binding protein (TBP), binds to ter sites, blocking the progress of DNA replication in a polar fashion, thus terminating replication . [More information is available at EcoCyc: EG11038].

Genomic context

Sequence:
NC_000913.3 (1684259..1685188)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional regulator RstA Neighboring gene sensory histidine kinase RstB Neighboring gene fumarase C Neighboring gene fumarase A Neighboring gene mannose-6-phosphate isomerase

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
DNA replication IEA
Inferred from Electronic Annotation
more info
 
DNA replication termination IDA
Inferred from Direct Assay
more info
PubMed 
DNA replication termination IEA
Inferred from Electronic Annotation
more info
 
replication fork arrest involved in DNA replication termination IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DNA replication terminus site-binding protein

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1684259..1685188
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416127.1 DNA replication terminus site-binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416127.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P16525
    Conserved Domains (1) summary
    PRK02951
    Location:1309
    PRK02951; DNA replication terminus site-binding protein; Provisional
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