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tus DNA replication terminus site-binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945135, updated on 11-Oct-2018

Summary

Gene symbol
tus
Gene description
DNA replication terminus site-binding protein
Primary source
EcoGene:EG11038
Locus tag
b1610
See related
ASAP:ABE-0005378; ECOCYC:EG11038
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1605; tau
Summary
Site-specific DNA binding protein Tus arrests the DnaB helicase at six chromosomal Ter sites (A-F), blocking replication forks. [More information is available at EcoGene: EG11038]. Tus, also known as ter-binding protein (TBP), binds to ter sites, blocking the progress of DNA replication in a polar fashion, thus terminating replication . [More information is available at EcoCyc: EG11038].

Genomic context

Sequence:
NC_000913.3 (1684259..1685188)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional regulator RstA Neighboring gene sensory histidine kinase RstB Neighboring gene fumarase C Neighboring gene fumarase A Neighboring gene mannose-6-phosphate isomerase

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
DNA replication terminus site-binding protein

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1684259..1685188
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416127.1 DNA replication terminus site-binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416127.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P16525
    Conserved Domains (1) summary
    PRK02951
    Location:1309
    PRK02951; DNA replication terminus site-binding protein; Provisional
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