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tesA multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945127, updated on 9-Mar-2022

Summary

Gene symbol
tesA
Gene description
multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1
Primary source
ASAP:ABE-0001713
Locus tag
b0494
See related
ECOCYC:EG11542
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
apeA; ECK0488; pldC
Summary
The TAP complex (TesA) is a broad-specificity esterase that carries out thioesterase, arylesterase, lyophospholipase, and protease activities. [More information is available at EcoCyc: EG11542].
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Genomic context

Sequence:
NC_000913.3 (519139..519765, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative iron ABC exporter ATP-binding subunit FetA Neighboring gene putative iron ABC exporter membrane subunit FetB Neighboring gene chaperedoxin Neighboring gene NADP(+)-dependent aldehyde reductase YbbO Neighboring gene putative ABC transporter ATP-binding protein YbbA Neighboring gene putative ABC transporter membrane subunit YbbP Neighboring gene protein RhsD

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables acyl-CoA hydrolase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables acyl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyl-[acyl-carrier-protein] hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables arylesterase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables lipase activity IEA
Inferred from Electronic Annotation
more info
 
enables lysophospholipase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables lysophospholipase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables lysophospholipase activity IEA
Inferred from Electronic Annotation
more info
 
enables myristoyl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables myristoyl-[acyl-carrier-protein] hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables oleoyl-[acyl-carrier-protein] hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables palmitoyl-CoA hydrolase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables palmitoyl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables palmitoyl-[acyl-carrier-protein] hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidyl phospholipase B activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1
NP_415027.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    519139..519765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415027.1 multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415027.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0ADA1
    Conserved Domains (1) summary
    PRK10528
    Location:18208
    PRK10528; multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1; Provisional