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crl [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945077, updated on 24-Aug-2024

Summary

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Official Symbol
crl
Primary source
ECOCYC:EG11092
Locus tag
b0240
See related
ASAP:ABE-0000821
Gene type
pseudo
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0241
Summary
RpoD, RpoS and RpoH sigma factor-containing holoenzyme assembly is stimulated by Crl (Gaal, 2006). [More information is available at EcoGene: EG11092]. Crl regulates the activity and abundance of the RNA polymerase component sigma S. [More information is available at EcoCyc: EG11092].
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Genomic context

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Sequence:
NC_000913.3 (257829..259006)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene xanthine-guanine phsophoribosyltransferase Neighboring gene fermentation-respiration switch protein Neighboring gene IS1 family transposase B Neighboring gene IS1 family repressor TnpA Neighboring gene outer membrane porin PhoE Neighboring gene glutamate 5-kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of crl in avian pathogenic Escherichia coli: a knockout mutation of crl does not affect hemagglutination activity, fibronectin binding, or Curli production. Provence DL, et al. Infect Immun, 1992 Nov. PMID 1398960, Free PMC Article
  2. Newly identified genetic variations in common Escherichia coli MG1655 stock cultures. Freddolino PL, et al. J Bacteriol, 2012 Jan. PMID 22081388, Free PMC Article
  3. Crl, a low temperature-induced protein in Escherichia coli that binds directly to the stationary phase sigma subunit of RNA polymerase. Bougdour A, et al. J Biol Chem, 2004 May 7. PMID 14978043
  4. Fibronectin binding mediated by a novel class of surface organelles on Escherichia coli. Olsén A, et al. Nature, 1989 Apr 20. PMID 2649795
  5. Biofilm formation by and multicellular behavior of Escherichia coli O55:H7, an atypical enteropathogenic strain. Weiss-Muszkat M, et al. Appl Environ Microbiol, 2010 Mar. PMID 20080991, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Recently identified mutations that are likely to cause loss of function of the glpR and crl genes, which may have serious implications for physiological experiments using the affected strains, are reported.
    Title: Newly identified genetic variations in common Escherichia coli MG1655 stock cultures.
  2. The csgFG and crl mutants were deficient in their biofilm formation capabilities and did not form a pellicle at the air-liquid interface.
    Title: Biofilm formation by and multicellular behavior of Escherichia coli O55:H7, an atypical enteropathogenic strain.
  3. N-terminus verified by Edman degradation on mature peptide
    Title: Fibronectin binding mediated by a novel class of surface organelles on Escherichia coli.
  4. role of Crl in regulating the expression of the proteome
    Title: The Crl-RpoS regulon of Escherichia coli.
  5. Crl has a global regulatory effect in stationary phase gene expression exclusively through sigma(S), that is, on sigma(S)-dependent genes only.
    Title: Stationary phase reorganisation of the Escherichia coli transcription machinery by Crl protein, a fine-tuner of sigmas activity and levels.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Miscellaneous features

  • Loc: 257829-257899 gene fragment 1 of crl
  • Loc: 258676-259006 gene fragment 2 of crl

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