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phoA alkaline phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945041, updated on 9-Mar-2022

Summary

Gene symbol
phoA
Gene description
alkaline phosphatase
Primary source
ASAP:ABE-0001328
Locus tag
b0383
See related
ECOCYC:EG10727
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0378; psiA
Summary
Arg22 is removed from the mature enzyme by Iap to form isozyme 3. [More information is available at EcoGene: EG10727]. Alkaline phosphatase is a dimer that occurs in three forms, depending upon the growth conditions of the cell. [More information is available at EcoCyc: EG10727].
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Genomic context

Sequence:
NC_000913.3 (401747..403162)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene D-alanine--D-alanine ligase A Neighboring gene anti-adaptor protein IraP Neighboring gene phosphate starvation-inducible protein PsiF Neighboring gene diguanylate cyclase DgcC

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables alkaline phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables alkaline phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables alkaline phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrogenase (acceptor) activity IDA
Inferred from Direct Assay
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on phosphorus or arsenic in donors IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphoprotein phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    401747..403162
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414917.2 alkaline phosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414917.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P00634
    Conserved Domains (1) summary
    PRK10518
    Location:1471
    PRK10518; alkaline phosphatase; Provisional