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lptD lipopolysaccharide assembly protein LptD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945011, updated on 19-Sep-2024

Summary

Official Symbol
lptD
Official Full Name
lipopolysaccharide assembly protein LptD
Primary source
ECOCYC:EG11569
Locus tag
b0054
See related
ASAP:ABE-0000183
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0055; imp; ostA; yabG
Summary
The outer membrane of an lptD(imp) mutant is permeable to large maltodextrins and sensitive to antibiotics and detergents. lptD is stress induced. [More information is available at EcoGene: EG11569]. The LptD (Increased membrane permeability) protein is an essential outer membrane (OM) protein which is involved with lipopolysaccharide assembly in the outer membrane as part of the outer membrane LPS assembly complex with RlpB . [More information is available at EcoCyc: EG11569].
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Genomic context

Sequence:
NC_000913.3 (54755..57109, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 16S rRNA m(6)2A1518,m(6)2A1519 dimethyltransferase Neighboring gene 4-hydroxythreonine-4-phosphate dehydrogenase Neighboring gene chaperone SurA Neighboring gene co-chaperone protein DjlA Neighboring gene putative uncharacterized protein YabP Neighboring gene protein YabQ

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cell outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cell outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell outer membrane IEA
Inferred from Electronic Annotation
more info
 
located_in cell outer membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of transporter complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of transporter complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
lipopolysaccharide assembly protein LptD
NP_414596.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    54755..57109 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414596.1 lipopolysaccharide assembly protein LptD [Escherichia coli str. K-12 substr. MG1655]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7H9NGN5
    Conserved Domains (1) summary
    PRK03761
    Location:1782
    PRK03761; LPS assembly outer membrane complex protein LptD; Provisional