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lacZ beta-galactosidase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945006, updated on 2-May-2024

Summary

Gene symbol
lacZ
Gene description
beta-galactosidase
Primary source
ASAP:ABE-0001183
Locus tag
b0344
See related
ECOCYC:EG10527
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0341
Summary
Repressed during biofilm formation. [More information is available at EcoGene: EG10527]. galacotsidase is a metalloenzyme exhibiting broad substrate specificity. [More information is available at EcoCyc: EG10527].
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Genomic context

Sequence:
NC_000913.3 (363231..366305, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene galactoside O-acetyltransferase Neighboring gene lactose permease Neighboring gene DNA-binding transcriptional repressor LacI Neighboring gene DNA-binding transcriptional activator MhpR

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables alkali metal ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables beta-galactosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables beta-galactosidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables beta-galactosidase activity IEA
Inferred from Electronic Annotation
more info
 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in lactose catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within lactose catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in lactose catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of beta-galactosidase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of beta-galactosidase complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of beta-galactosidase complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
beta-galactosidase
NP_414878.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    363231..366305 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414878.1 beta-galactosidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414878.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376X5J4
    Conserved Domains (1) summary
    PRK09525
    Location:11024
    lacZ; beta-galactosidase