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tdcR DNA-binding transcriptional activator TdcR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944907, updated on 6-Jul-2026
Official Symbol
tdcR
Official Full Name
DNA-binding transcriptional activator TdcR
Primary source
ECOCYC:EG10992
Locus tag
b3119
See related
ASAP:ABE-0010255
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3108
Summary
During anaerobiosis, TdcR participates in controlling several genes involved in transport and metabolism of threonine and serine . [More information is available at EcoCyc: EG10992].
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Sequence:
NC_000913.3 (3267380..3267598)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene catabolic threonine dehydratase Neighboring gene DNA-binding transcriptional activator TdcA Neighboring gene protein YhaB Neighboring gene uncharacterized protein YhaC

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Escherichia coli K-12 mutation that inactivates biodegradative threonine dehydratase by transposon Tn5 insertion. Goss TJ, et al. J Bacteriol, 1984 Jun. PMID 6327641, Free PMC Article
  2. Identification and DNA sequence of tdcR, a positive regulatory gene of the tdc operon of Escherichia coli. Schweizer HP, et al. Mol Gen Genet, 1989 Sep. PMID 2573820
  3. Physical linkage and transcriptional orientation of the tdc operon on the Escherichia coli chromosome. Schweizer HP, et al. Mol Gen Genet, 1991 Aug. PMID 1886605
  4. Structure and function of enzymes involved in the anaerobic degradation of L-threonine to propionate. Simanshu DK, et al. J Biosci, 2007 Sep. PMID 17954980
  5. A novel mechanism controls anaerobic and catabolite regulation of the Escherichia coli tdc operon. Sawers G. Mol Microbiol, 2001 Mar. PMID 11251844

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
DNA-binding transcriptional activator TdcR

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3267380..3267598
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417589.4 DNA-binding transcriptional activator TdcR

    See identical proteins and their annotated locations for NP_417589.4

    Status: REVIEWED

    Conserved Domains (1) summary
    PRK11424
    Location:1 → 72
    PRK11424; DNA-binding transcriptional activator TdcR; Provisional
Nucleotide Protein
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