ldcC lysine decarboxylase 2 [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: ldcC
Official Full Name: lysine decarboxylase 2
Primary source: ECOCYC:G6094
Locus tag: b0186
See related: ASAP:ABE-0000633
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK0185; ldc; ldcH
Summary: There are two lysine decarboxylases in Escherichia coli, encoded by the cadA and ldcC genes . [More information is available at EcoCyc: G6094].
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NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Cadaverine biosynthesis contributes to decreased Escherichia coli susceptibility to antibiotics.
Title: Cadaverine biosynthesis contributes to decreased Escherichia coli susceptibility to antibiotics.
This study reveals that EcLdcC is a promising whole-cell biocatalyst for the bio-based production of cadaverine from industrial grade L-lysine in comparison to EcCadA.
Title: Characterization of a Whole-Cell Biotransformation Using a Constitutive Lysine Decarboxylase from Escherichia coli for the High-Level Production of Cadaverine from Industrial Grade L-Lysine.
The structural principles of the LdcI-RavA interaction are being described using molecular modeling.
Title: Assembly principles of a unique cage formed by hexameric and decameric E. coli proteins.
N-terminus verified by Edman degradation on complete protein
Title: The Escherichia coli ldcC gene encodes another lysine decarboxylase, probably a constitutive enzyme.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables carboxy-lyase activity	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IDA Inferred from Direct Assay more info	PubMed
enables identical protein binding	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables lysine decarboxylase activity	IDA Inferred from Direct Assay more info	PubMed
enables lysine decarboxylase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed