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sufD Fe-S cluster scaffold complex subunit SufD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944878, updated on 17-Jul-2025
Official Symbol
sufD
Official Full Name
Fe-S cluster scaffold complex subunit SufD
Primary source
ECOCYC:G6907
Locus tag
b1681
See related
ASAP:ABE-0005617
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1677; ynhC
Summary
SufB and SufD are homologous. [More information is available at EcoGene: EG13963]. The SufB-SufC-SufD complex activates the cysteine desulfurase activity SufS in conjunction with the SufE sulfur acceptor protein . [More information is available at EcoCyc: G6907].
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Sequence:
NC_000913.3 (1760520..1761791, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene L,D-transpeptidase LdtE Neighboring gene sulfur carrier protein SufE Neighboring gene L-cysteine desulfurase Neighboring gene Fe-S cluster scaffold complex subunit SufC Neighboring gene Fe-S cluster scaffold complex subunit SufB Neighboring gene iron-sulfur cluster insertion protein SufA

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Iron-sulfur (Fe-S) cluster assembly: the SufBCD complex is a new type of Fe-S scaffold with a flavin redox cofactor. Wollers S, et al. J Biol Chem, 2010 Jul 23. PMID 20460376, Free PMC Article
  2. Molecular dynamism of Fe-S cluster biosynthesis implicated by the structure of the SufC(2)-SufD(2) complex. Wada K, et al. J Mol Biol, 2009 Mar 20. PMID 19361433, Free PMC Article
  3. The SufBCD Fe-S scaffold complex interacts with SufA for Fe-S cluster transfer. Chahal HK, et al. Biochemistry, 2009 Nov 10. PMID 19810706, Free PMC Article
  4. The SufE protein and the SufBCD complex enhance SufS cysteine desulfurase activity as part of a sulfur transfer pathway for Fe-S cluster assembly in Escherichia coli. Outten FW, et al. J Biol Chem, 2003 Nov 14. PMID 12941942
  5. Induction of the sufA operon encoding Fe-S assembly proteins by superoxide generators and hydrogen peroxide: involvement of OxyR, IHF and an unidentified oxidant-responsive factor. Lee JH, et al. Mol Microbiol, 2004 Mar. PMID 15009899

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in iron-sulfur cluster assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within iron-sulfur cluster assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in iron-sulfur cluster assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within iron-sulfur cluster assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in iron-sulfur cluster assembly NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of iron-sulfur cluster assembly complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of iron-sulfur cluster assembly complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of iron-sulfur cluster assembly complex IPI
Inferred from Physical Interaction
more info
 PubMed 
Preferred Names
Fe-S cluster scaffold complex subunit SufD

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1760520..1761791 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416196.1 Fe-S cluster scaffold complex subunit SufD

    See identical proteins and their annotated locations for NP_416196.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6N8NLL4
    Conserved Domains (1) summary
    PRK10948
    Location:1 → 423
    PRK10948; Fe-S cluster assembly protein SufD
Nucleotide Protein
Heading Accession and Version

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