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sufD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944878, updated on 24-Aug-2024

Summary

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Official Symbol
sufD
Primary source
ECOCYC:G6907
Locus tag
b1681
See related
ASAP:ABE-0005617
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1677; ynhC
Summary
SufB and SufD are homologous. [More information is available at EcoGene: EG13963]. The SufB-SufC-SufD complex activates the cysteine desulfurase activity SufS in conjunction with the SufE sulfur acceptor protein . [More information is available at EcoCyc: G6907].
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Genomic context

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Sequence:
NC_000913.3 (1760520..1761791, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene L,D-transpeptidase LdtE Neighboring gene sulfur carrier protein SufE Neighboring gene L-cysteine desulfurase Neighboring gene Fe-S cluster scaffold complex subunit SufC Neighboring gene Fe-S cluster scaffold complex subunit SufB Neighboring gene iron-sulfur cluster insertion protein SufA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Iron-sulfur (Fe-S) cluster assembly: the SufBCD complex is a new type of Fe-S scaffold with a flavin redox cofactor. Wollers S, et al. J Biol Chem, 2010 Jul 23. PMID 20460376, Free PMC Article
  2. Molecular dynamism of Fe-S cluster biosynthesis implicated by the structure of the SufC(2)-SufD(2) complex. Wada K, et al. J Mol Biol, 2009 Mar 20. PMID 19361433, Free PMC Article
  3. The SufBCD Fe-S scaffold complex interacts with SufA for Fe-S cluster transfer. Chahal HK, et al. Biochemistry, 2009 Nov 10. PMID 19810706, Free PMC Article
  4. Induction of the sufA operon encoding Fe-S assembly proteins by superoxide generators and hydrogen peroxide: involvement of OxyR, IHF and an unidentified oxidant-responsive factor. Lee JH, et al. Mol Microbiol, 2004 Mar. PMID 15009899
  5. The SufE protein and the SufBCD complex enhance SufS cysteine desulfurase activity as part of a sulfur transfer pathway for Fe-S cluster assembly in Escherichia coli. Outten FW, et al. J Biol Chem, 2003 Nov 14. PMID 12941942

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within iron-sulfur cluster assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in iron-sulfur cluster assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within iron-sulfur cluster assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in iron-sulfur cluster assembly NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of iron-sulfur cluster assembly complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of iron-sulfur cluster assembly complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
Fe-S cluster scaffold complex subunit SufD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1760520..1761791 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416196.1 Fe-S cluster scaffold complex subunit SufD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416196.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6N8NLL4
    Conserved Domains (1) summary
    PRK10948
    Location:1 → 423
    PRK10948; Fe-S cluster assembly protein SufD
Nucleotide Protein
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