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lpd lipoamide dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944854, updated on 9-Mar-2022

Summary

Gene symbol
lpd
Gene description
lipoamide dehydrogenase
Primary source
ASAP:ABE-0000404
Locus tag
b0116
See related
ECOCYC:EG10543
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
dhl; ECK0115; lpdA
Summary
Holoenzyme is AceE(24)+AceF(24)+Lpd(12). [More information is available at EcoGene: EG10543]. Lipoamide dehydrogenase is the E3 component of three multicomponent enzyme complexes: |FRAME: [More information is available at EcoCyc: EG10543].
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Genomic context

Sequence:
NC_000913.3 (127912..129336)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pyruvate dehydrogenase E1 component Neighboring gene pyruvate dehydrogenase, E2 subunit Neighboring gene DUF3300 domain-containing protein YacH Neighboring gene AcnB

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables dihydrolipoyl dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables dihydrolipoyl dehydrogenase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables dihydrolipoyl dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
enables disulfide oxidoreductase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables flavin adenine dinucleotide binding IDA
Inferred from Direct Assay
more info
PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol HDA PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytosolic pyruvate dehydrogenase complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
lipoamide dehydrogenase
NP_414658.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    127912..129336
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414658.1 lipoamide dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414658.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A9P0
    Conserved Domains (1) summary
    PRK06467
    Location:3472
    PRK06467; dihydrolipoamide dehydrogenase; Reviewed