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wzzE enterobacterial common antigen polysaccharide co-polymerase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944815, updated on 9-Mar-2022

Summary

Gene symbol
wzzE
Gene description
enterobacterial common antigen polysaccharide co-polymerase
Primary source
ASAP:ABE-0012370
Locus tag
b3785
See related
ECOCYC:EG11295
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3777; wzz; yifC
Summary
Mutants have elevated OM vesiculation (McBroom, 2006). [More information is available at EcoGene: EG11295]. WzzE is responsible for regulating the length of phosphoglyceride-linked Enterobacterial Common Antigen (ECAPG) polysaccharide chains formed from polymerization by WzyE utilizing Lipid III in the periplasm. [More information is available at EcoCyc: EG11295].
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Genomic context

Sequence:
NC_000913.3 (3969031..3970077)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene transcription termination factor Rho Neighboring gene UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase Neighboring gene UDP-N-acetylglucosamine 2-epimerase Neighboring gene UDP-N-acetyl-D-mannosamine dehydrogenase Neighboring gene dTDP-glucose 4,6-dehydratase 2

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
located_in integral component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
enterobacterial common antigen polysaccharide co-polymerase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3969031..3970077
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418232.2 enterobacterial common antigen polysaccharide co-polymerase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418232.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AG00
    Conserved Domains (1) summary
    PRK11638
    Location:8348
    PRK11638; ECA polysaccharide chain length modulation protein