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cfa cyclopropane fatty acyl phospholipid synthase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944811, updated on 9-Mar-2022

Summary

Gene symbol
cfa
Gene description
cyclopropane fatty acyl phospholipid synthase
Primary source
ASAP:ABE-0005555
Locus tag
b1661
See related
ECOCYC:EG11531
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
cdfA; ECK1657
Summary
Cfa binds a bicarbonate ion that is involved in catalysis. [More information is available at EcoGene: EG11531]. Cyclopropane fatty acyl phospholipid synthase (CFA) catalyzes a modification of the acyl chains of phospholipid bilayers through methylenation of unsaturated fatty acyl chains to their cyclopropane derivatives . [More information is available at EcoCyc: EG11531].
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Genomic context

Sequence:
NC_000913.3 (1741413..1742561)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional repressor PurR Neighboring gene DNA-binding transcriptional activator PunR Neighboring gene purine nucleoside transporter PunC Neighboring gene riboflavin synthase Neighboring gene multidrug efflux pump MdtK

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables bicarbonate binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cyclopropane-fatty-acyl-phospholipid synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables cyclopropane-fatty-acyl-phospholipid synthase activity IEA
Inferred from Electronic Annotation
more info
 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in lipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipid modification IDA
Inferred from Direct Assay
more info
PubMed 
involved_in methylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
cyclopropane fatty acyl phospholipid synthase
NP_416178.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1741413..1742561
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416178.1 cyclopropane fatty acyl phospholipid synthase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416178.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A9H7
    Conserved Domains (1) summary
    PRK11705
    Location:1382
    PRK11705; cyclopropane fatty acyl phospholipid synthase