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fkpB peptidyl-prolyl cis-trans isomerase FkpB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944807, updated on 19-Nov-2025
Official Symbol
fkpB
Official Full Name
peptidyl-prolyl cis-trans isomerase FkpB
Primary source
ECOCYC:EG11080
Locus tag
b0028
See related
ASAP:ABE-0000101
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0029; slpA; yaaD
Summary
FkpB is a FK506-binding protein type of peptidyl-prolyl cis/trans-isomerases (PPIase) . [More information is available at EcoCyc: EG11080].
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Sequence:
NC_000913.3 (25826..26275)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene isoleucine--tRNA ligase Neighboring gene lipoprotein signal peptidase Neighboring gene 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Neighboring gene ribonucleoside hydrolase RihC

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. High-resolution insights into binding of unfolded polypeptides by the PPIase chaperone SlpA. Quistgaard EM, et al. FASEB J, 2012 Oct. PMID 22735173
  2. The Escherichia coli SlyD is a metal ion-regulated peptidyl-prolyl cis/trans-isomerase. Hottenrott S, et al. J Biol Chem, 1997 Jun 20. PMID 9188461
  3. Nucleotide sequence of the Escherichia coli prolipoprotein signal peptidase (lsp) gene. Innis MA, et al. Proc Natl Acad Sci U S A, 1984 Jun. PMID 6374664, Free PMC Article
  4. Mapping of the lipoprotein signal peptidase gene (lsp). Regue M, et al. J Bacteriol, 1984 May. PMID 6373724, Free PMC Article
  5. Identification of prolipoprotein signal peptidase and genomic organization of the lsp gene in Escherichia coli. Tokunaga M, et al. J Biol Chem, 1985 May 10. PMID 2580835

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidyl-prolyl cis-trans isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptidyl-prolyl cis-trans isomerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables peptidyl-prolyl cis-trans isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
peptidyl-prolyl cis-trans isomerase FkpB
NP_414569.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    25826..26275
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414569.1 peptidyl-prolyl cis-trans isomerase FkpB

    See identical proteins and their annotated locations for NP_414569.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2X1KW22
    Conserved Domains (1) summary
    PRK15095
    Location:1 → 149
    PRK15095; FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional
Nucleotide Protein
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