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sgrR DNA-binding transcriptional dual regulator SgrR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944788, updated on 6-Jul-2026
Official Symbol
sgrR
Official Full Name
DNA-binding transcriptional dual regulator SgrR
Primary source
ECOCYC:EG12094
Locus tag
b0069
See related
ASAP:ABE-0000251
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0070; yabN
Summary
"SugaR transport-related Regulator" SgrR is negatively autoregulated and coordinately activates transcription of the divergent operon. [More information is available at EcoCyc: EG12094].
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Sequence:
NC_000913.3 (75644..77299, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene thiamine ABC transporter membrane subunit Neighboring gene thiamine ABC transporter periplasmic binding protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene PtsG glucose transporter inhibitor Neighboring gene sugar exporter SetA

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Physiological consequences of small RNA-mediated regulation of glucose-phosphate stress. Vanderpool CK. Curr Opin Microbiol, 2007 Apr. PMID 17383224
  2. Systematic sequencing of the Escherichia coli genome: analysis of the 0-2.4 min region. Yura T, et al. Nucleic Acids Res, 1992 Jul 11. PMID 1630901, Free PMC Article
  3. The novel transcription factor SgrR coordinates the response to glucose-phosphate stress. Vanderpool CK, et al. J Bacteriol, 2007 Mar. PMID 17209026, Free PMC Article
  4. Involvement of a novel transcriptional activator and small RNA in post-transcriptional regulation of the glucose phosphoenolpyruvate phosphotransferase system. Vanderpool CK, et al. Mol Microbiol, 2004 Nov. PMID 15522088
  5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SgrR negatively autoregulates its own transcription in the presence and absence of glucose-phosphate stress.
    Title: The novel transcription factor SgrR coordinates the response to glucose-phosphate stress.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables peptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription cis-regulatory region binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in peptide transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional dual regulator SgrR

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    75644..77299 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414611.1 DNA-binding transcriptional dual regulator SgrR

    See identical proteins and their annotated locations for NP_414611.1

    Status: REVIEWED

    Conserved Domains (1) summary
    PRK13626
    Location:1 → 551
    PRK13626; HTH-type transcriptional regulator SgrR
Nucleotide Protein
Heading Accession and Version

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Other Literature Sources
Molecular Biology Databases
Research Materials