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thiP thiamine ABC transporter membrane subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944784, updated on 23-Nov-2023

Summary

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Gene symbol
thiP
Gene description
thiamine ABC transporter membrane subunit
Primary source
ASAP:ABE-0000246
Locus tag
b0067
See related
ECOCYC:EG11573
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0068; sfuB; yabK
Summary
[More information is available at EcoGene: EG11573]. The ABC transporter ThiBPQ was functionally characterized in Salmonella typhimurium where it is required for the uptake of thiamine and thiamine pyrophosphate . [More information is available at EcoCyc: EG11573].
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Genomic context

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Sequence:
NC_000913.3 (72911..74521, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator AraC Neighboring gene DedA family protein YabI Neighboring gene thiamine ABC transporter ATP binding subunit Neighboring gene thiamine ABC transporter periplasmic binding protein Neighboring gene ncRNA Neighboring gene DNA-binding transcriptional dual regulator SgrR

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Thiamine transport in Escherichia coli: the mechanism of inhibition by the sulfhydryl-specific modifier N-ethylmaleimide. Hollenbach AD, et al. Biochim Biophys Acta, 2002 Aug 31. PMID 12175925
  2. Counterflow efflux of thiamin in Escherichia coli. Nishimune T, et al. Biochim Biophys Acta, 1981 Dec 7. PMID 7032593
  3. Active transport of [32P]thiamine diphosphate in Escherichia coli. Nishimune T, et al. Experientia, 1980 Aug 15. PMID 7002582
  4. Thiamine-binding protein and thiamine uptake by Escherichia coli. Nishimune T, et al. Biochim Biophys Acta, 1971 Sep 21. PMID 4946194
  5. Thiamine uptake in Escherichia coli. I. General properties of thiamine uptake system in Escherichia coli. Kawasaki T, et al. Arch Biochem Biophys, 1969 Apr. PMID 4889357

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables thiamine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within thiamine transmembrane transport ISO
Inferred from Sequence Orthology
more info
 PubMed 
involved_in thiamine transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in thiamine transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
thiamine ABC transporter membrane subunit
NP_414609.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    72911..74521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414609.1 thiamine ABC transporter membrane subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414609.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7F9E0
    Conserved Domains (1) summary
    PRK09433
    Location:11 → 535
    thiP; thiamine transporter membrane protein; Reviewed
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases