Format

Send to:

Choose Destination

nhaA Na(+):H(+) antiporter NhaA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944758, updated on 6-May-2021

Summary

Gene symbol
nhaA
Gene description
Na(+):H(+) antiporter NhaA
Primary source
ASAP:ABE-0000068
Locus tag
b0019
See related
ECOCYC:EG10652
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ant; antA; ECK0020
Summary
nhaA P2 promoter is RpoS-regulated, but H-NS, Na(+)- and NhaR-independent. [More information is available at EcoGene: EG10652]. NhaA is a sodium ion/proton antiporter that uses the proton electrochemical gradient to expel sodium ions from the cytoplasm and functions primarily in the adaptation to high salinity at alkaline pH. [More information is available at EcoCyc: EG10652].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (17489..18655)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein HokC Neighboring gene regulatory protein MokC Neighboring gene ncRNA Neighboring gene DNA-binding transcriptional activator NhaR Neighboring gene IS1 protein InsB Neighboring gene IS1 protein InsA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
 
enables cardiolipin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables sodium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables sodium:proton antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables sodium:proton antiporter activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    17489..18655
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414560.1 Na(+):H(+) antiporter NhaA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414560.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P13738
    Conserved Domains (1) summary
    PRK09561
    Location:1388
    nhaA; sodium/proton antiporter NhaA
Support Center