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Prcc papillary renal cell carcinoma (translocation-associated) [ Mus musculus (house mouse) ]

Gene ID: 94315, updated on 5-Mar-2024

Summary

Official Symbol
Prccprovided by MGI
Official Full Name
papillary renal cell carcinoma (translocation-associated)provided by MGI
Primary source
MGI:MGI:2137738
See related
Ensembl:ENSMUSG00000004895 AllianceGenome:MGI:2137738
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in regulation of cell cycle. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Human ortholog(s) of this gene implicated in papillary renal cell carcinoma. Orthologous to human PRCC (proline rich mitotic checkpoint control factor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 21.0), CNS E14 (RPKM 18.7) and 28 other tissues See more
Orthologs
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Genomic context

See Prcc in Genome Data Viewer
Location:
3 F1; 3 38.78 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (87766210..87792869, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (87858903..87885562, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32470 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:87650795-87651072 Neighboring gene SH2 domain containing 2A Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:87689595-87689778 Neighboring gene STARR-seq mESC enhancer starr_08164 Neighboring gene STARR-seq mESC enhancer starr_08165 Neighboring gene heparin binding growth factor Neighboring gene STARR-positive B cell enhancer ABC_E10190 Neighboring gene mitochondrial ribosomal protein L24 Neighboring gene methyltransferase like 25B

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033573.2NP_291051.1  proline-rich protein PRCC

    See identical proteins and their annotated locations for NP_291051.1

    Status: VALIDATED

    Source sequence(s)
    BC052072
    Consensus CDS
    CCDS17456.1
    UniProtKB/TrEMBL
    Q05CA9, Q9EQC8
    Related
    ENSMUSP00000005015.9, ENSMUST00000005015.10
    Conserved Domains (1) summary
    pfam10253
    Location:366491
    PRCC; Mitotic checkpoint regulator, MAD2B-interacting

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    87766210..87792869 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)