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SFXN5 sideroflexin 5 [ Homo sapiens (human) ]

Gene ID: 94097, updated on 11-Jun-2021

Summary

Official Symbol
SFXN5provided by HGNC
Official Full Name
sideroflexin 5provided by HGNC
Primary source
HGNC:HGNC:16073
See related
Ensembl:ENSG00000144040 MIM:615572
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BBG-TCC; SLC56A5
Expression
Broad expression in brain (RPKM 13.0), liver (RPKM 3.8) and 20 other tissues See more
Orthologs
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Genomic context

See SFXN5 in Genome Data Viewer
Location:
2p13.2
Exon count:
19
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (72942036..73071712, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (73169165..73298841, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr2.2721 Neighboring gene zinc finger MYM-type containing 1 pseudogene Neighboring gene empty spiracles homeobox 1 Neighboring gene Sharpr-MPRA regulatory region 2442 Neighboring gene uncharacterized LOC107985897 Neighboring gene Sharpr-MPRA regulatory region 10332 Neighboring gene uncharacterized LOC105374800 Neighboring gene RAB11 family interacting protein 5 Neighboring gene notochord homeobox

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC120413, MGC120415

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables citrate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in citrate transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in integral component of mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330400.2NP_001317329.1  sideroflexin-5 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:32315
    Mtc; Tricarboxylate carrier
  2. NM_001330401.2NP_001317330.1  sideroflexin-5 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Consensus CDS
    CCDS82469.1
    UniProtKB/TrEMBL
    B8ZZJ6
    Related
    ENSP00000387076.1, ENST00000410065.5
    Conserved Domains (1) summary
    pfam03820
    Location:32213
    Mtc; Tricarboxylate carrier
  3. NM_001330402.2NP_001317331.1  sideroflexin-5 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:32278
    Mtc; Tricarboxylate carrier
  4. NM_001330403.2NP_001317332.1  sideroflexin-5 isoform 5 precursor

    Status: VALIDATED

    Source sequence(s)
    AC012366
  5. NM_001330404.2NP_001317333.1  sideroflexin-5 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:1236
    Mtc; Tricarboxylate carrier
  6. NM_001330405.2NP_001317334.1  sideroflexin-5 isoform 7 precursor

    Status: VALIDATED

    Source sequence(s)
    AC012366
  7. NM_001330406.2NP_001317335.1  sideroflexin-5 isoform 8 precursor

    Status: VALIDATED

    Source sequence(s)
    AC012366
  8. NM_001330407.2NP_001317336.1  sideroflexin-5 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:1211
    Mtc; Tricarboxylate carrier
  9. NM_001330408.2NP_001317337.1  sideroflexin-5 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:1174
    Mtc; Tricarboxylate carrier
  10. NM_001330410.2NP_001317339.1  sideroflexin-5 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Related
    ENST00000474528.5
    Conserved Domains (1) summary
    pfam03820
    Location:1236
    Mtc; Tricarboxylate carrier
  11. NM_001330411.2NP_001317340.1  sideroflexin-5 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC012366
    UniProtKB/TrEMBL
    B4DIJ8
  12. NM_001330412.2NP_001317341.1  sideroflexin-5 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC012366
    UniProtKB/TrEMBL
    B4DIJ8
  13. NM_001371737.1NP_001358666.1  sideroflexin-5 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:57338
    Mtc; Tricarboxylate carrier
  14. NM_001371738.1NP_001358667.1  sideroflexin-5 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:38319
    Mtc; Tricarboxylate carrier
  15. NM_001371739.1NP_001358668.1  sideroflexin-5 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:36317
    Mtc; Tricarboxylate carrier
  16. NM_001371740.1NP_001358669.1  sideroflexin-5 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:32247
    Mtc; Tricarboxylate carrier
  17. NM_001371741.1NP_001358670.1  sideroflexin-5 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Related
    ENSP00000402141.1, ENST00000411783.5
    Conserved Domains (1) summary
    pfam03820
    Location:27212
    Mtc; Tricarboxylate carrier
  18. NM_001371742.1NP_001358671.1  sideroflexin-5 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:32208
    Mtc; Tricarboxylate carrier
  19. NM_001371743.1NP_001358672.1  sideroflexin-5 isoform 18

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Conserved Domains (1) summary
    pfam03820
    Location:32198
    Mtc; Tricarboxylate carrier
  20. NM_144579.3NP_653180.1  sideroflexin-5 isoform 2

    See identical proteins and their annotated locations for NP_653180.1

    Status: VALIDATED

    Source sequence(s)
    AC012366
    Consensus CDS
    CCDS1922.1
    UniProtKB/Swiss-Prot
    Q8TD22
    Related
    ENSP00000272433.2, ENST00000272433.7
    Conserved Domains (1) summary
    pfam03820
    Location:27340
    Mtc; Tricarboxylate carrier

RNA

  1. NR_138476.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC012366

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    72942036..73071712 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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