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SYAP1 synapse associated protein 1 [ Homo sapiens (human) ]

Gene ID: 94056, updated on 21-Dec-2019

Summary

Official Symbol
SYAP1provided by HGNC
Official Full Name
synapse associated protein 1provided by HGNC
Primary source
HGNC:HGNC:16273
See related
Ensembl:ENSG00000169895
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BSTA; PRO3113
Expression
Ubiquitous expression in adrenal (RPKM 23.9), colon (RPKM 16.3) and 25 other tissues See more
Orthologs

Genomic context

See SYAP1 in Genome Data Viewer
Location:
Xp22.2
Exon count:
9
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (16719612..16765340)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (16737707..16780807)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene CTP synthase 2 Neighboring gene microRNA 548am Neighboring gene S100 calcium binding protein G Neighboring gene RNA, U7 small nuclear 56 pseudogene Neighboring gene taxilin gamma Neighboring gene RB binding protein 7, chromatin remodeling factor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14495, FLJ44185, DKFZp686K221

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
 
axon ISS
Inferred from Sequence or Structural Similarity
more info
 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
 
dendrite ISS
Inferred from Sequence or Structural Similarity
more info
 
extracellular exosome HDA PubMed 
extrinsic component of cytoplasmic side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
growth cone ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
perikaryon ISS
Inferred from Sequence or Structural Similarity
more info
 
perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
postsynaptic membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
presynaptic membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
synapse-associated protein 1
Names
BSD domain-containing signal transducer and Akt interactor protein
SAP47 homolog
synapse associated protein 1, SAP47 homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016374.1 RefSeqGene

    Range
    5001..48101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_032796.4NP_116185.2  synapse-associated protein 1

    See identical proteins and their annotated locations for NP_116185.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.
    Source sequence(s)
    AA829759, AF168955, AF305828, AL445467, DB047379, DB577454
    Consensus CDS
    CCDS14177.1
    UniProtKB/Swiss-Prot
    Q96A49
    Related
    ENSP00000369500.3, ENST00000380155.4
    Conserved Domains (1) summary
    smart00751
    Location:160210
    BSD; domain in transcription factors and synapse-associated proteins

RNA

  1. NR_033181.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in an internal exon compared to variant 1. It is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AA829759, AK303783, AL445467, DB047379

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    16719612..16765340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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