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FTMT ferritin mitochondrial [ Homo sapiens (human) ]

Gene ID: 94033, updated on 1-Aug-2020

Summary

Official Symbol
FTMTprovided by HGNC
Official Full Name
ferritin mitochondrialprovided by HGNC
Primary source
HGNC:HGNC:17345
See related
Ensembl:ENSG00000181867 MIM:608847
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MTF
Orthologs

Genomic context

See FTMT in Genome Data Viewer
Location:
5q23.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (121851882..121852833)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (121187650..121188528)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ribosomal L24 domain containing 1 pseudogene 10 Neighboring gene uncharacterized LOC105379150 Neighboring gene uncharacterized LOC105379149 Neighboring gene uncharacterized LOC105379148 Neighboring gene serum response factor binding protein 1 Neighboring gene lysyl oxidase

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide association study (GWAS) for bronchopulmonary dysplasia.
NHGRI GWA Catalog
Genetic variation modifies risk for neurodegeneration based on biomarker status.
NHGRI GWA Catalog
Genome-wide association studies and heritability estimates of body mass index related phenotypes in bangladeshi adults.
NHGRI GWA Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ferric iron binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ferrous iron binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ferroxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
iron ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cellular iron ion homeostasis IDA
Inferred from Direct Assay
more info
PubMed 
cellular iron ion homeostasis TAS
Traceable Author Statement
more info
 
intracellular sequestering of iron ion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
iron ion transport IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of aconitate hydratase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of lyase activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of succinate dehydrogenase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial matrix TAS
Traceable Author Statement
more info
 
nucleus HDA PubMed 

General protein information

Preferred Names
ferritin, mitochondrial
Names
ferritin H subunit
mitochondrial ferritin
NP_803431.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177478.2NP_803431.1  ferritin, mitochondrial precursor

    See identical proteins and their annotated locations for NP_803431.1

    Status: VALIDATED

    Source sequence(s)
    AC117523, BC034419
    Consensus CDS
    CCDS4128.1
    UniProtKB/Swiss-Prot
    Q8N4E7
    Related
    ENSP00000313691.1, ENST00000321339.3
    Conserved Domains (2) summary
    cd01056
    Location:73233
    Euk_Ferritin; eukaryotic ferritins
    pfam00210
    Location:77218
    Ferritin; Ferritin-like domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    121851882..121852833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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