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nrdE ribonucleoside-diphosphate reductase (major subunit) [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 940091, updated on 4-Feb-2024

Summary

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Gene symbol
nrdE
Gene description
ribonucleoside-diphosphate reductase (major subunit)
Locus tag
BSU_17380
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU17380
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Genomic context

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Sequence:
NC_000964.3 (1868969..1871071)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene co-factor of ribonucleotide diphosphate reductase Neighboring gene ribonucleoside-diphosphate reductase (minor subunit) Neighboring gene putative cofactor involved in deoxyribonucleotide synthesis

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Bacillus subtilis nrdEF genes, encoding a class Ib ribonucleotide reductase, are essential for aerobic and anaerobic growth. Härtig E, et al. Appl Environ Microbiol, 2006 Aug. PMID 16885274, Free PMC Article
  2. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  3. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
  4. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article
  5. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Kunst F, et al. Nature, 1997 Nov 20. PMID 9384377

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. essential for aerobic and anaerobic growth and transcription.
    Title: The Bacillus subtilis nrdEF genes, encoding a class Ib ribonucleotide reductase, are essential for aerobic and anaerobic growth.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
ribonucleoside-diphosphate reductase (major subunit)
NP_389620.1
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15937154, 16885274, 17395719, 21561096, 22443445, 23402532, 24401092, 27920297; Product type e: enzyme

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_389620.1 ribonucleoside-diphosphate reductase (major subunit) [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_389620.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    D4FWY0
    Conserved Domains (1) summary
    PRK07632
    Location:1 → 700
    PRK07632; ribonucleotide-diphosphate reductase subunit alpha; Validated
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P50620.1

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases