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pksJ polyketide synthase of type I involved in nonribosomal synthesis of bacillaene [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 940043, updated on 4-Feb-2024
Gene symbol
pksJ
Gene description
polyketide synthase of type I involved in nonribosomal synthesis of bacillaene
Locus tag
BSU_17180
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU17180
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Sequence:
NC_000964.3 (1792806..1807937)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene acetyl-S-AcpK beta-ketothioester bacillaene intermediate transferase Neighboring gene enoyl-CoA hydratase for bacillaene biosynthesis Neighboring gene decarboxylase involved in bacillaene synthesis Neighboring gene polyketide synthase of type I (bacillaene synthesis) Neighboring gene trans AT polyketide synthase of type I involved in bacillaene synthesis Neighboring gene trans AT polyketide synthase of type I involved in bacillaene synthesis

Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase. Gay DC, et al. Structure, 2014 Mar 4. PMID 24508341, Free PMC Article
  2. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  3. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
  4. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article
  5. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Kunst F, et al. Nature, 1997 Nov 20. PMID 9384377

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Polyketide synthase structure explains its substrate specificity.
    Title: A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.
Submit: New GeneRIF Correction

Homology

Preferred Names
polyketide synthase of type I involved in nonribosomal synthesis of bacillaene
NP_389598.3
  • Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 16707694, 17234808, 17827323, 26284661, 26268540; Product type e: enzyme

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_389598.3 polyketide synthase of type I involved in nonribosomal synthesis of bacillaene [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_389598.3

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    U5U6Q0
    Conserved Domains (6) summary
    cd08953
    Location:2673 → 3083
    KR_2_SDR_x; ketoreductase (KR), subgroup 2, complex (x) SDRs
    smart00823
    Location:3112 → 3186
    PKS_PP; Phosphopantetheine attachment site
    COG3321
    Location:3340 → 4371
    PksD; Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]
    PRK12467
    Location:185 → 1738
    PRK12467; peptide synthase; Provisional
    cd05906
    Location:20 → 561
    A_NRPS_TubE_like; The adenylation domain (A domain) of a family of nonribosomal peptide synthetases (NRPSs) synthesizing toxins and antitumor agents
    pfam00550
    Location:4466 → 4526
    PP-binding; Phosphopantetheine attachment site
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40806.3

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases