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pksR trans AT polyketide synthase involved in nonribosomal synthesis of bacillaene [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 940036, updated on 10-Oct-2024
Gene symbol
pksR
Gene description
trans AT polyketide synthase involved in nonribosomal synthesis of bacillaene
Locus tag
BSU_17220
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU17220
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Sequence:
NC_000964.3 (1850890..1858521)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene trans AT polyketide synthase of type I involved in bacillaene synthesis Neighboring gene trans AT polyketide synthase of type I involved in bacillaene synthesis Neighboring gene cytochrome P450 of bacillaene metabolism Neighboring gene conserved protein of unknown function involved in ethanol resistance

Genomic Sequence:
NC_000964.3
Preferred Names
trans AT polyketide synthase involved in nonribosomal synthesis of bacillaene
NP_389604.2
  • Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 10960106, 15480790, 16707694, 17234808, 22720735, 26284661; Product type e : enzyme

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_389604.2 trans AT polyketide synthase involved in nonribosomal synthesis of bacillaene [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_389604.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAP1ECU5
    Conserved Domains (7) summary
    smart00823
    Location:375449
    PKS_PP; Phosphopantetheine attachment site
    COG3319
    Location:22342518
    EntF; Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism]
    COG3321
    Location:15282209
    PksD; Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]
    cd00833
    Location:528957
    PKS; polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or ...
    pfam08242
    Location:165262
    Methyltransf_12; Methyltransferase domain
    pfam16197
    Location:9431030
    KAsynt_C_assoc; Ketoacyl-synthetase C-terminal extension
    cl00509
    Location:11321391
    hot_dog; The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated ...