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pksM trans AT polyketide synthase of type I involved in bacillaene synthesis [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 940026, updated on 6-Oct-2023
Gene symbol
pksM
Gene description
trans AT polyketide synthase of type I involved in bacillaene synthesis
Locus tag
BSU_17200
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU17200
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Sequence:
NC_000964.3 (1821553..1834341)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene decarboxylase involved in bacillaene synthesis Neighboring gene polyketide synthase of type I involved in nonribosomal synthesis of bacillaene Neighboring gene polyketide synthase of type I (bacillaene synthesis) Neighboring gene trans AT polyketide synthase of type I involved in bacillaene synthesis Neighboring gene trans AT polyketide synthase involved in nonribosomal synthesis of bacillaene

Genomic Sequence:
NC_000964.3
Preferred Names
trans AT polyketide synthase of type I involved in bacillaene synthesis
NP_389601.3
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15480790, 16707694, 17234808, 26284661; Product type e: enzyme

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_389601.3 trans AT polyketide synthase of type I involved in bacillaene synthesis [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_389601.3

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    U5U6S4
    Conserved Domains (6) summary
    cd08953
    Location:13641750
    KR_2_SDR_x; ketoreductase (KR), subgroup 2, complex (x) SDRs
    COG3321
    Location:3911508
    PksD; Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]
    pfam00550
    Location:298358
    PP-binding; Phosphopantetheine attachment site
    pfam08242
    Location:19892067
    Methyltransf_12; Methyltransferase domain
    cl00509
    Location:18268
    hot_dog; The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated ...
    cl09938
    Location:18932120
    cond_enzymes; Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the ...