U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gyrA DNA gyrase (subunit A) [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 940002, updated on 17-Dec-2024

Summary

Go to the top of the page Help
Gene symbol
gyrA
Gene description
DNA gyrase (subunit A)
Locus tag
BSU_00070
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU00070
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000964.3 (6994..9459)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene regulator of extracellular matrix formation Neighboring gene DNA gyrase (subunit B) Neighboring gene ribosomal RNA-16S Neighboring gene tRNA-Ile

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The acidic C-terminal tail of the GyrA subunit moderates the DNA supercoiling activity of Bacillus subtilis gyrase. Lanz MA, et al. J Biol Chem, 2014 May 2. PMID 24563461, Free PMC Article
  2. DNA gyrase activity regulates DnaA-dependent replication initiation in Bacillus subtilis. Samadpour AN, et al. Mol Microbiol, 2018 Apr. PMID 29396913, Free PMC Article
  3. Dissection of the nucleotide cycle of B. subtilis DNA gyrase and its modulation by DNA. Göttler T, et al. J Mol Biol, 2007 Apr 13. PMID 17320901
  4. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  5. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DNA gyrase is a negative regulator of DnaA-dependent replication initiation from oriC, and that this regulatory mechanism is required for cell survival.
    Title: DNA gyrase activity regulates DnaA-dependent replication initiation in Bacillus subtilis.
  2. Data indicate that eletion of the acidic C-terminal tail causes stronger DNA bending by the gyrase C-terminal domains and accelerated DNA-stimulated ATPase and supercoiling activities of gyrase.
    Title: The acidic C-terminal tail of the GyrA subunit moderates the DNA supercoiling activity of Bacillus subtilis gyrase.
  3. The active heterotetramer of B. subtilis DNA gyrase is formed by mixing the GyrA and GyrB subunits.
    Title: Dissection of the nucleotide cycle of B. subtilis DNA gyrase and its modulation by DNA.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

General protein information

Go to the top of the page Help
Preferred Names
DNA gyrase (subunit A)
NP_387888.1
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 12767818, 17320901, 27557712; Product type e: enzyme

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_387888.1 DNA gyrase (subunit A) [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_387888.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5D4N6I1
    Conserved Domains (2) summary
    PRK05560
    Location:8 → 806
    PRK05560; DNA gyrase subunit A; Validated
    sd00041
    Location:505 → 552
    GyrA-ParC_C; GyrA_CTD repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P05653.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases