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Hemgn hemogen [ Mus musculus (house mouse) ]

Gene ID: 93966, updated on 26-Sep-2022

Summary

Official Symbol
Hemgnprovided by MGI
Official Full Name
hemogenprovided by MGI
Primary source
MGI:MGI:2136910
See related
Ensembl:ENSMUSG00000028332 AllianceGenome:MGI:2136910
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hgn; EDAG; mNDR; 4921524M03Rik
Summary
Predicted to be involved in regulation of osteoblast differentiation. Located in nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver. Orthologous to human HEMGN (hemogen). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver E14 (RPKM 190.3), liver E14.5 (RPKM 184.7) and 3 other tissues See more
Orthologs
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Genomic context

See Hemgn in Genome Data Viewer
Location:
4; 4 B1
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (46393989..46404183, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (46393989..46404183, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene forkhead box E1 Neighboring gene tRNA methyltransferase O Neighboring gene acidic (leucine-rich) nuclear phosphoprotein 32 family, member B Neighboring gene predicted gene, 22247 Neighboring gene N-acetylneuraminic acid synthase (sialic acid synthase)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (4)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of osteoblast differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of osteoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
hemogen
Names
hemopoietic gene protein
negative differentiation regulator protein
nuclear protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053149.2NP_444379.1  hemogen

    See identical proteins and their annotated locations for NP_444379.1

    Status: PROVISIONAL

    Source sequence(s)
    AL683884
    Consensus CDS
    CCDS18150.1
    UniProtKB/Swiss-Prot
    Q8CF29, Q9ERZ0
    Related
    ENSMUSP00000103393.3, ENSMUST00000107764.9

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    46393989..46404183 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)