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GCNA germ cell nuclear acidic peptidase [ Homo sapiens (human) ]

Gene ID: 93953, updated on 5-Mar-2024

Summary

Official Symbol
GCNAprovided by HGNC
Official Full Name
germ cell nuclear acidic peptidaseprovided by HGNC
Primary source
HGNC:HGNC:15805
See related
Ensembl:ENSG00000147174 MIM:300369; AllianceGenome:HGNC:15805
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ACRC; NAAR1; SPGFX4
Summary
Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 6.8), adrenal (RPKM 2.2) and 12 other tissues See more
Orthologs
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Genomic context

See GCNA in Genome Data Viewer
Location:
Xq13.1
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (71578437..71613583)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (70011688..70046833)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (70798287..70833433)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene TATA-box binding protein associated factor 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chrX:70752005-70753204 Neighboring gene SOCS6 pseudogene 1 Neighboring gene O-linked N-acetylglucosamine (GlcNAc) transferase Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:70798494-70799135 Neighboring gene Sharpr-MPRA regulatory region 14051 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29746 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29745 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29747 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29748 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29749 Neighboring gene Sharpr-MPRA regulatory region 2992 Neighboring gene C-X-C motif chemokine receptor 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29750 Neighboring gene chromosome X open reading frame 49 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29751 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29752

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables SUMO polymer binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in protein-DNA covalent cross-linking repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in PML body IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
germ cell nuclear acidic protein
Names
acidic repeat containing
acidic repeat-containing protein
germ cell nuclear antigen
putative nuclear protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_052957.5NP_443189.1  germ cell nuclear acidic protein

    See identical proteins and their annotated locations for NP_443189.1

    Status: VALIDATED

    Source sequence(s)
    AL590763
    Consensus CDS
    CCDS35326.1
    UniProtKB/Swiss-Prot
    B9EG62, Q96QF7
    UniProtKB/TrEMBL
    B3KXM1
    Related
    ENSP00000362800.3, ENST00000373696.8
    Conserved Domains (1) summary
    smart00731
    Location:519677
    SprT; SprT homologues

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    71578437..71613583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    70011688..70046833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)