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birA biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor (BirA-biotinoyl-5'-AMP) [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 939028, updated on 4-Feb-2024

Summary

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Gene symbol
birA
Gene description
biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor (BirA-biotinoyl-5'-AMP)
Locus tag
BSU_22440
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU22440
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Genomic context

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Sequence:
NC_000964.3 (2354918..2355895, complement)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene pantothenate synthetase Neighboring gene ketopantoate hydroxymethyltransferase Neighboring gene tRNA nucleotidyltransferase Neighboring gene N-acetyl-alpha-D-glucosaminyl L-malate synthase; malate glycosyltransferase for bacillithiol synthesis Neighboring gene N-acetyl-alpha-D-glucosaminyl L-malate deacetylase 1; malate N-acetylglucosamine N-acetyl hydrolase Neighboring gene methylglyoxal synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved regulatory mechanism in bifunctional biotin protein ligases. Wang J, et al. Protein Sci, 2017 Aug. PMID 28466579, Free PMC Article
  2. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  3. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
  4. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article
  5. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Kunst F, et al. Nature, 1997 Nov 20. PMID 9384377

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor (BirA-biotinoyl-5'-AMP)
NP_390125.1
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12368242, 15459338, 28466579; Product type e: enzyme

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    2354918..2355895 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_390125.1 biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor (BirA-biotinoyl-5'-AMP) [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_390125.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    D4FY10
    Conserved Domains (2) summary
    COG1654
    Location:2 → 80
    BirA; Biotin operon repressor [Transcription]
    TIGR00121
    Location:85 → 325
    birA_ligase; birA, biotin-[acetyl-CoA-carboxylase] ligase region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CI75.1

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases
Research Materials