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Fzd10 frizzled class receptor 10 [ Mus musculus (house mouse) ]

Gene ID: 93897, updated on 12-May-2024

Summary

Official Symbol
Fzd10provided by MGI
Official Full Name
frizzled class receptor 10provided by MGI
Primary source
MGI:MGI:2136761
See related
Ensembl:ENSMUSG00000081683 AllianceGenome:MGI:2136761
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fz-10
Summary
Enables Wnt-protein binding activity. Acts upstream of or within Wnt signaling pathway. Predicted to be located in cell surface; cytoplasm; and nucleoplasm. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human FZD10 (frizzled class receptor 10). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Fzd10 in Genome Data Viewer
Location:
5 G1.3; 5 67.67 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (128678170..128681157)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (128601106..128604093)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38612 Neighboring gene frizzled class receptor 10, opposite strand Neighboring gene STARR-seq mESC enhancer starr_14425 Neighboring gene STARR-seq mESC enhancer starr_14426 Neighboring gene predicted gene, 33931 Neighboring gene STARR-seq mESC enhancer starr_14427 Neighboring gene predicted gene, 33995

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables Wnt receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables Wnt receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables Wnt-protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables Wnt-protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
frizzled-10
Names
frizzled homolog 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175284.3NP_780493.1  frizzled-10 precursor

    See identical proteins and their annotated locations for NP_780493.1

    Status: PROVISIONAL

    Source sequence(s)
    AY509002
    Consensus CDS
    CCDS51652.1
    UniProtKB/Swiss-Prot
    Q8BKG4
    UniProtKB/TrEMBL
    Q149J3, Q71S95
    Related
    ENSMUSP00000114114.3, ENSMUST00000117102.4
    Conserved Domains (2) summary
    pfam01534
    Location:219536
    Frizzled; Frizzled/Smoothened family membrane region
    cl02447
    Location:31157
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    128678170..128681157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)