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hxlR positive regulator of hxlAB expression (formaldehyde sensing) [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 938311, updated on 6-Jun-2024

Summary

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Gene symbol
hxlR
Gene description
positive regulator of hxlAB expression (formaldehyde sensing)
Locus tag
BSU_03470
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU03470
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Genomic context

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Sequence:
NC_000964.3 (376032..376394)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene 6-phospho-3-hexuloisomerase (PHI) Neighboring gene 3-hexulose-6-phosphate synthase (HPS) Neighboring gene surfactin synthetase Neighboring gene surfactin synthetase Neighboring gene regulator of genetic competence

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HxlR, a member of the DUF24 protein family, is a DNA-binding protein that acts as a positive regulator of the formaldehyde-inducible hxlAB operon in Bacillus subtilis. Yurimoto H, et al. Mol Microbiol, 2005 Jul. PMID 15978081
  2. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  3. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
  4. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article
  5. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Kunst F, et al. Nature, 1997 Nov 20. PMID 9384377

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. findings show that HxlR is a DNA-binding protein that is necessary for formaldehyde-induced expression of hxlAB in B. subtilis.
    Title: HxlR, a member of the DUF24 protein family, is a DNA-binding protein that acts as a positive regulator of the formaldehyde-inducible hxlAB operon in Bacillus subtilis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
positive regulator of hxlAB expression (formaldehyde sensing)
NP_388229.2
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 15978081, 26973631; Product type r: regulator

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_388229.2 positive regulator of hxlAB expression (formaldehyde sensing) [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_388229.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    D4G514
    Conserved Domains (1) summary
    pfam01638
    Location:19 → 109
    HxlR; HxlR-like helix-turn-helix
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P42406.3

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases
Research Materials