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trxA thioredoxin [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 938187, updated on 12-Feb-2021

Summary

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Gene symbol
trxA
Gene description
thioredoxin
Locus tag
BSU_28500
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU28500
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Genomic context

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Sequence:
NC_000964.3 (2913024..2913338, complement)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene excinuclease ABC (subunit C) Neighboring gene pseudo Neighboring gene exo-alpha-L-arabinofuranosidase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Extracytoplasmic processes impaired by inactivation of trxA (thioredoxin gene) in Bacillus subtilis. Möller MC, et al. J Bacteriol, 2008 Jul. PMID 18456801, Free PMC Article
  2. Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis. Li Y, et al. J Biol Chem, 2007 Apr 13. PMID 17303556
  3. Tricksy business: transcriptome analysis reveals the involvement of thioredoxin A in redox homeostasis, oxidative stress, sulfur metabolism, and cellular differentiation in Bacillus subtilis. Smits WK, et al. J Bacteriol, 2005 Jun. PMID 15937154, Free PMC Article
  4. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  5. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show taht inactivation of trxA results in deoxyribonucleoside and cysteine or methionine auxotrophy, and in defects in endospore and cytochrome c synthesis.
    Title: Extracytoplasmic processes impaired by inactivation of trxA (thioredoxin gene) in Bacillus subtilis.
  2. We report the effects of minimal induction of a strain carrying an IPTG (isopropyl-beta-D-thiogalactopyranoside)-inducible trxA gene (ItrxA) on transcription levels.
    Title: Tricksy business: transcriptome analysis reveals the involvement of thioredoxin A in redox homeostasis, oxidative stress, sulfur metabolism, and cellular differentiation in Bacillus subtilis.
  3. provide novel insights into understanding the reaction mechanisms of the thioredoxin-arsenate reductase pathway
    Title: Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
thioredoxin
NP_390728.1
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9537387, 12682299, 1459769, 15937154, 17303556, 18455736, 18601268; Product type c: carrier

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    2913024..2913338 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_390728.1 thioredoxin [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_390728.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P14949
    Conserved Domains (1) summary
    TIGR01068
    Location:6 → 104
    thioredoxin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P14949.3

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases
Research Materials