U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

sppA signal peptide peptidase [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 937679, updated on 10-Feb-2026
Gene symbol
sppA
Gene description
signal peptide peptidase
Locus tag
BSU_29530
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU29530
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_000964.3 (3020040..3021047, complement)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene conserved sporulation-related protein Neighboring gene putative integral inner membrane protein Neighboring gene inorganic polyphosphate/ATP-NAD kinase Neighboring gene putative N-substituted formamide deformylase, dihydropyrimidinase or isoaspartyl peptidase

Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structure of signal peptide peptidase A with C-termini bound in the active sites: insights into specificity, self-processing, and regulation. Nam SE, et al. Biochemistry, 2013 Dec 10. PMID 24228759
  2. Crystal structure of Bacillus subtilis signal peptide peptidase A. Nam SE, et al. J Mol Biol, 2012 Jun 22. PMID 22472423
  3. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  4. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
  5. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The C-terminus of Bacillus subtilis sppA binds within the substrate-binding grooves in an antiparallel beta-sheet fashion.
    Title: Structure of signal peptide peptidase A with C-termini bound in the active sites: insights into specificity, self-processing, and regulation.
  2. The 2.4-A-resolution structure of Bacillus subtilis SppA (SppA(BS)) catalytic domain reveals eight SppA(BS) molecules in the asymmetric unit, forming a dome-shaped octameric complex.
    Title: Crystal structure of Bacillus subtilis signal peptide peptidase A.
Submit: New GeneRIF Correction

Homology

Preferred Names
signal peptide peptidase
NP_390831.1
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9987136, 10455123, 16484219, 22472423, 23155385, 24228759; Product type e : enzyme

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    3020040..3021047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_390831.1 signal peptide peptidase [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_390831.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AC61ZZD8
    Conserved Domains (1) summary
    TIGR00706
    Location:59 → 280
    SppA_dom; signal peptide peptidase SppA, 36K type
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O34525.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials