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mccA cystathionine beta-synthase for the reverse transsulfuration pathway [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 937576, updated on 12-Feb-2021

Summary

Gene symbol
mccA
Gene description
cystathionine beta-synthase for the reverse transsulfuration pathway
Locus tag
BSU_27260
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU27260
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Genomic context

Sequence:
NC_000964.3 (2786142..2787065, complement)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway Neighboring gene methylthioadenosine / S-adenosylhomocysteine nucleosidase Neighboring gene putative AdoMet-dependent methyltransferase

Pathways from PubChem

General protein information

Preferred Names
cystathionine beta-synthase for the reverse transsulfuration pathway
NP_390604.1
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10939241, 15760717, 17056751, 18812398; Product type e: enzyme

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    2786142..2787065 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_390604.1 cystathionine beta-synthase for the reverse transsulfuration pathway [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_390604.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O05393
    Conserved Domains (1) summary
    cd01561
    Location:12299
    CBS_like; This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of ...
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