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niaR transcriptional repressor of de novo NAD biosynthesis [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 937515, updated on 4-Feb-2024

Summary

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Gene symbol
niaR
Gene description
transcriptional repressor of de novo NAD biosynthesis
Locus tag
BSU_27890
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU27890
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Genomic context

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Sequence:
NC_000964.3 (2850716..2851258)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene quinolinate synthetase Neighboring gene nicotinate-nucleotide pyrophosphorylase (quinolinate phosphoribosyltransferase) Neighboring gene L-aspartate oxidase Neighboring gene desulfurase involved in iron-sulfur clusters for NAD biosynthesis Neighboring gene prephenate dehydratase Neighboring gene transcriptional repressor of operons hom-thrCB and thrD

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. YrxA is the transcriptional regulator that represses de novo NAD biosynthesis in Bacillus subtilis. Rossolillo P, et al. J Bacteriol, 2005 Oct. PMID 16199587, Free PMC Article
  2. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  3. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
  4. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article
  5. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Kunst F, et al. Nature, 1997 Nov 20. PMID 9384377

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. YrxA is the regulator of NAD de novo biosynthesis in Bacillus subtilis
    Title: YrxA is the transcriptional regulator that represses de novo NAD biosynthesis in Bacillus subtilis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
transcriptional repressor of de novo NAD biosynthesis
NP_390667.2
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 16199587, 18276644; Product type r: regulator

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_390667.2 transcriptional repressor of de novo NAD biosynthesis [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_390667.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    D4FZJ5
    Conserved Domains (1) summary
    COG1827
    Location:7 → 178
    NiaR; Transcriptional regulator of NAD metabolism, contains HTH and 3H domains [Transcription, Coenzyme transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P39667.2

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases