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epr extracellular serine protease [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 937332, updated on 4-Feb-2024

Summary

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Gene symbol
epr
Gene description
extracellular serine protease
Locus tag
BSU_38400
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU38400
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Genomic context

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Sequence:
NC_000964.3 (3939869..3941806)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene putative cellobiose phosphotransferase system enzyme IIC permease component Neighboring gene negative regulator of SacY Neighboring gene transcriptional antiterminator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The carboxy terminal domain of Epr, a minor extracellular serine protease, is essential for the swarming motility of Bacillus subtilis 168. Murudkar CS, et al. FEMS Microbiol Lett, 2006 Apr. PMID 16553828
  2. Spo0A positively regulates epr expression by negating the repressive effect of co-repressors, SinR and ScoC, in Bacillus subtilis. Gupta M, et al. J Biosci, 2013 Jun. PMID 23660663
  3. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  4. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
  5. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Spo0A binds to the upstream region of epr promoter and in turn occludes the binding site of one of the co-repressor, SinR.
    Title: Spo0A positively regulates epr expression by negating the repressive effect of co-repressors, SinR and ScoC, in Bacillus subtilis.
  2. Expression of Epr-CTD (C-terminal domain) as well as its secretion is required for the swarming motility of B. subtilis 168.
    Title: The carboxy terminal domain of Epr, a minor extracellular serine protease, is essential for the swarming motility of Bacillus subtilis 168.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
extracellular serine protease
NP_391719.1
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 1938892, 2116590, 16553828, 17666034, 19416356, 23660663, 25966269; Product type e: enzyme

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_391719.1 extracellular serine protease [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_391719.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    D4G328
    Conserved Domains (3) summary
    PTZ00121
    Location:390 → 645
    PTZ00121; MAEBL; Provisional
    cd07477
    Location:135 → 358
    Peptidases_S8_Subtilisin_subset; Peptidase S8 family domain in Subtilisin proteins
    COG1404
    Location:3 → 470
    AprE; Serine protease, subtilisin family [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P16396.1

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases