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parC subunit A of DNA topoisomerase IV (ATP-dependent) [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 937107, updated on 6-Oct-2023

Summary

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Gene symbol
parC
Gene description
subunit A of DNA topoisomerase IV (ATP-dependent)
Locus tag
BSU_18100
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU18100
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Genomic context

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Sequence:
NC_000964.3 (1935448..1937868)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene putative acyl-CoA-binding protein Neighboring gene subunit B of DNA topoisomerase IV (ATP-dependent) Neighboring gene pseudo Neighboring gene pseudo Neighboring gene H+/Na+:nitrogen-donor aminoacid symporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Topoisomerase IV can functionally replace all type 1A topoisomerases in Bacillus subtilis. Reuß DR, et al. Nucleic Acids Res, 2019 Jun 4. PMID 30957856, Free PMC Article
  2. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  3. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
  4. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article
  5. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Kunst F, et al. Nature, 1997 Nov 20. PMID 9384377

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. topoisomerase IV at increased expression is necessary and sufficient to take over the function of type 1A topoisomerases
    Title: Topoisomerase IV can functionally replace all type 1A topoisomerases in Bacillus subtilis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
subunit A of DNA topoisomerase IV (ATP-dependent)
NP_389692.2
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9539793, 12682299, 16267290, 16272394, 24440393; Product type e: enzyme

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_389692.2 subunit A of DNA topoisomerase IV (ATP-dependent) [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_389692.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0D1L394
    Conserved Domains (2) summary
    TIGR01061
    Location:7 → 744
    parC_Gpos; DNA topoisomerase IV, A subunit, Gram-positive
    sd00041
    Location:504 → 546
    GyrA-ParC_C; GyrA_CTD repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q45066.2

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases