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degS two-component sensor histidine kinase [DegU] [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 936752, updated on 6-Oct-2023

Summary

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Gene symbol
degS
Gene description
two-component sensor histidine kinase [DegU]
Locus tag
BSU_35500
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU35500
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Genomic context

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Sequence:
NC_000964.3 (3645379..3646536, complement)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene fatty acid kinase fatty acid binding subunit A Neighboring gene two-component response regulator Neighboring gene putative translation regulator Neighboring gene teichoic acid-peptidoglycan tethering enzyme (LCP component) with transcription regulator domain

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Bacillus subtilis two-component system sensory kinase DegS is regulated by serine phosphorylation in its input domain. Jers C, et al. PLoS One, 2011 Feb 3. PMID 21304896, Free PMC Article
  2. Gradual activation of the response regulator DegU controls serial expression of genes for flagellum formation and biofilm formation in Bacillus subtilis. Kobayashi K. Mol Microbiol, 2007 Oct. PMID 17850253
  3. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  4. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
  5. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A link between DegS phosphorylation at serine 76 and the level of DegU phosphorylation, establishing this post-translational modification as an additional trigger for this two-component system.
    Title: Bacillus subtilis two-component system sensory kinase DegS is regulated by serine phosphorylation in its input domain.
  2. Results show that degS mutation did not affect transcription of the flgB-sigD operon, but reduced transcription of sigma(D)-dependent flagellar genes, degU and other DegU-regulated genes.
    Title: Gradual activation of the response regulator DegU controls serial expression of genes for flagellum formation and biofilm formation in Bacillus subtilis.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
two-component sensor histidine kinase [DegU]
NP_391430.1
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 10908654, 11557812, 12471443, 12950930, 14563871, 15342569, 15598897, 17590234, 17827323, 21736639, 22677979, 24847778, 25288929, 25880922, 25887289, 27920766; Product type rc : receptor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    3645379..3646536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_391430.1 two-component sensor histidine kinase [DegU] [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_391430.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0D1J0Q7
    Conserved Domains (1) summary
    COG4585
    Location:1 → 383
    COG4585; Signal transduction histidine kinase [Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P13799.2

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases
Research Materials