U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RAB33A RAB33A, member RAS oncogene family [ Homo sapiens (human) ]

Gene ID: 9363, updated on 5-Aug-2022

Summary

Official Symbol
RAB33Aprovided by HGNC
Official Full Name
RAB33A, member RAS oncogene familyprovided by HGNC
Primary source
HGNC:HGNC:9773
See related
Ensembl:ENSG00000134594 MIM:300333; AllianceGenome:HGNC:9773
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RabS10
Summary
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is GTP-binding protein and may be involved in vesicle transport. [provided by RefSeq, Jul 2008]
Expression
Biased expression in brain (RPKM 10.9), lymph node (RPKM 3.6) and 7 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See RAB33A in Genome Data Viewer
Location:
Xq26.1
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (130110623..130184870)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (128490768..128503675)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (129305936..129318844)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373335 Neighboring gene UTP14A small subunit processome component Neighboring gene BCL6 corepressor like 1 Neighboring gene uncharacterized LOC124905216 Neighboring gene E74 like ETS transcription factor 4 Neighboring gene apoptosis inducing factor mitochondria associated 1 Neighboring gene zinc finger protein 280C Neighboring gene RNA, U6 small nuclear 1130, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC1488

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in Rab protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in antigen processing and presentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi membrane TAS
Traceable Author Statement
more info
 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ras-related protein Rab-33A
Names
Small GTP-binding protein S10

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012558.1 RefSeqGene

    Range
    5164..18072
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_004794.3NP_004785.1  ras-related protein Rab-33A

    See identical proteins and their annotated locations for NP_004785.1

    Status: REVIEWED

    Source sequence(s)
    BC001157
    Consensus CDS
    CCDS14621.1
    UniProtKB/Swiss-Prot
    Q14088, Q92465
    Related
    ENSP00000257017.4, ENST00000257017.5
    Conserved Domains (1) summary
    cd04115
    Location:35204
    Rab33B_Rab33A; Rab GTPase family 33 includes Rab33A and Rab33B

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    130110623..130184870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017029963.3XP_016885452.1  ras-related protein Rab-33A isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    128490768..128503675
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)