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GPR52 G protein-coupled receptor 52 [ Homo sapiens (human) ]

Gene ID: 9293, updated on 23-Nov-2021

Summary

Official Symbol
GPR52provided by HGNC
Official Full Name
G protein-coupled receptor 52provided by HGNC
Primary source
HGNC:HGNC:4508
See related
Ensembl:ENSG00000203737 MIM:604106
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Members of the G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied by OMIM, Jul 2002]
Orthologs
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Genomic context

See GPR52 in Genome Data Viewer
Location:
1q25.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (174447964..174449545)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (174417102..174418683)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 797 Neighboring gene RABGAP1L divergent transcript Neighboring gene RAB GTPase activating protein 1 like Neighboring gene forty-two-three domain containing 1 pseudogene Neighboring gene Sharpr-MPRA regulatory region 10542 Neighboring gene BANF1 pseudogene 4

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vif vif HIV-1 Vif downregulates the expression of G protein-coupled receptor 52 (GPR52) in Vif-expression T cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC111751

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled photoreceptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables G protein-coupled receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular response to light stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in detection of visible light IEA
Inferred from Electronic Annotation
more info
 
involved_in locomotory behavior ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in phototransduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in response to xenobiotic stimulus IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
G-protein coupled receptor 52
Names
probable G-protein coupled receptor 52

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005684.5NP_005675.3  G-protein coupled receptor 52

    See identical proteins and their annotated locations for NP_005675.3

    Status: VALIDATED

    Source sequence(s)
    AL022171, BC069460, BC095532, DA174341, DB168074
    Consensus CDS
    CCDS30941.1
    UniProtKB/Swiss-Prot
    Q9Y2T5
    UniProtKB/TrEMBL
    F2YGU0
    Related
    ENSP00000356658.2, ENST00000367685.5
    Conserved Domains (1) summary
    cd00637
    Location:43321
    7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    174447964..174449545
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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