Format

Send to:

Choose Destination

SHKBP1 SH3KBP1 binding protein 1 [ Homo sapiens (human) ]

Gene ID: 92799, updated on 4-Nov-2018

Summary

Official Symbol
SHKBP1provided by HGNC
Official Full Name
SH3KBP1 binding protein 1provided by HGNC
Primary source
HGNC:HGNC:19214
See related
Ensembl:ENSG00000160410 MIM:617322; Vega:OTTHUMG00000182602
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Sb1; PP203
Expression
Ubiquitous expression in bone marrow (RPKM 24.5), spleen (RPKM 23.9) and 25 other tissues See more
Orthologs

Genomic context

See SHKBP1 in Genome Data Viewer
Location:
19q13.2
Exon count:
18
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 19 NC_000019.10 (40576851..40591399)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (41082757..41097305)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene biliverdin reductase B Neighboring gene spectrin beta, non-erythrocytic 4 Neighboring gene latent transforming growth factor beta binding protein 4 Neighboring gene NUMB like, endocytic adaptor protein

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
positive regulation of epidermal growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of epidermal growth factor receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
protein homooligomerization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
lysosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
SH3KBP1-binding protein 1
Names
SETA-binding protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138392.3NP_612401.2  SH3KBP1-binding protein 1

    See identical proteins and their annotated locations for NP_612401.2

    Status: VALIDATED

    Source sequence(s)
    AF258553, BC007653, CA416700, DB038927
    Consensus CDS
    CCDS12560.1
    UniProtKB/Swiss-Prot
    Q8TBC3
    Related
    ENSP00000291842.4, OTTHUMP00000269627, ENST00000291842.9, OTTHUMT00000462613
    Conserved Domains (1) summary
    pfam02214
    Location:21106
    BTB_2; BTB/POZ domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p12 Primary Assembly

    Range
    40576851..40591399
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006723474.2XP_006723537.1  SH3KBP1-binding protein 1 isoform X1

    Conserved Domains (2) summary
    smart00225
    Location:23108
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam02214
    Location:21106
    BTB_2; BTB/POZ domain
  2. XM_006723475.2XP_006723538.1  SH3KBP1-binding protein 1 isoform X2

    Conserved Domains (2) summary
    smart00225
    Location:23108
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam02214
    Location:21106
    BTB_2; BTB/POZ domain
  3. XM_017027473.2XP_016882962.1  SH3KBP1-binding protein 1 isoform X3

  4. XM_011527492.2XP_011525794.1  SH3KBP1-binding protein 1 isoform X4

    Conserved Domains (2) summary
    smart00225
    Location:23108
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam02214
    Location:21106
    BTB_2; BTB/POZ domain
  5. XM_011527493.2XP_011525795.1  SH3KBP1-binding protein 1 isoform X5

  6. XM_017027474.2XP_016882963.1  SH3KBP1-binding protein 1 isoform X6

    UniProtKB/TrEMBL
    B3KVX8
Support Center