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CCPG1 cell cycle progression 1 [ Homo sapiens (human) ]

Gene ID: 9236, updated on 12-Oct-2019

Summary

Official Symbol
CCPG1provided by HGNC
Official Full Name
cell cycle progression 1provided by HGNC
Primary source
HGNC:HGNC:24227
See related
Ensembl:ENSG00000260916 MIM:611326
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CPR8
Expression
Ubiquitous expression in thyroid (RPKM 34.7), gall bladder (RPKM 22.2) and 25 other tissues See more
Orthologs

Genomic context

See CCPG1 in Genome Data Viewer
Location:
15q21.3
Exon count:
9
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (55355223..55408510, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (55647421..55700708, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene RAB27A, member RAS oncogene family Neighboring gene Sharpr-MPRA regulatory region 6285 Neighboring gene PIGB opposite strand 1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class B Neighboring gene DNAAF4-CCPG1 readthrough (NMD candidate) Neighboring gene microRNA 628 Neighboring gene chromosome 15 open reading frame 65 Neighboring gene thioesterase superfamily member 4 pseudogene Neighboring gene dynein axonemal assembly factor 4 Neighboring gene uncharacterized mitochondrial protein AtMg00860-like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough DNAAF4-CCPG1

Readthrough gene: DNAAF4-CCPG1, Included gene: DNAAF4

Homology

Clone Names

  • FLJ60574, KIAA1254

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
regulation of Rho guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
cell cycle progression protein 1
Names
cell cycle progression restoration protein 8

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204450.1NP_001191379.1  cell cycle progression protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001191379.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks a segment in the 3' coding region that results in a frameshift. The encoded isoform (2) has a distinct and longer C-terminus, compared to isoform 1.
    Source sequence(s)
    AA740595, AC018926, AK292795, DB084778
    Consensus CDS
    CCDS55966.1
    UniProtKB/Swiss-Prot
    Q9ULG6
    Related
    ENSP00000403400.3, ENST00000442196.7
    Conserved Domains (1) summary
    pfam05837
    Location:313401
    CENP-H; Centromere protein H (CENP-H)
  2. NM_001204451.1NP_001191380.1  cell cycle progression protein 1 isoform 3

    See identical proteins and their annotated locations for NP_001191380.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks two segments in the 3' coding region, one of which causes a frameshift. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AA740595, AC018926, AK022459, DB084778
    Consensus CDS
    CCDS55967.1
    UniProtKB/Swiss-Prot
    Q9ULG6
    Related
    ENSP00000415128.3, ENST00000425574.7
    Conserved Domains (2) summary
    PLN02328
    Location:84231
    PLN02328; lysine-specific histone demethylase 1 homolog
    pfam04375
    Location:195321
    HemX; HemX
  3. NM_004748.5NP_004739.3  cell cycle progression protein 1 isoform 1

    See identical proteins and their annotated locations for NP_004739.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1. Both variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AA740595, AC018926, BC039871, DA670725, DA720583
    Consensus CDS
    CCDS42039.1
    UniProtKB/Swiss-Prot
    Q9ULG6
    UniProtKB/TrEMBL
    A0A024R5S7
    Related
    ENSP00000454456.1, ENST00000569205.5
    Conserved Domains (1) summary
    pfam05837
    Location:313401
    CENP-H; Centromere protein H (CENP-H)
  4. NM_020739.4NP_065790.2  cell cycle progression protein 1 isoform 1

    See identical proteins and their annotated locations for NP_065790.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AA740595, AC018926, BC039871, DB084778
    Consensus CDS
    CCDS42039.1
    UniProtKB/Swiss-Prot
    Q9ULG6
    UniProtKB/TrEMBL
    A0A024R5S7
    Related
    ENSP00000311656.6, ENST00000310958.10
    Conserved Domains (1) summary
    pfam05837
    Location:313401
    CENP-H; Centromere protein H (CENP-H)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    55355223..55408510 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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