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MEX3A mex-3 RNA binding family member A [ Homo sapiens (human) ]

Gene ID: 92312, updated on 28-Nov-2021

Summary

Official Symbol
MEX3Aprovided by HGNC
Official Full Name
mex-3 RNA binding family member Aprovided by HGNC
Primary source
HGNC:HGNC:33482
See related
Ensembl:ENSG00000254726 MIM:611007
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RKHD4; MEX-3A; RNF162
Expression
Broad expression in endometrium (RPKM 3.0), ovary (RPKM 2.6) and 16 other tissues See more
Orthologs
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Genomic context

See MEX3A in Genome Data Viewer
Location:
1q22
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (156072013..156082465, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (156041804..156052256, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Neighboring gene RAB25, member RAS oncogene family Neighboring gene Sharpr-MPRA regulatory region 8324 Neighboring gene Sharpr-MPRA regulatory region 15377 Neighboring gene lamin A/C Neighboring gene VISTA enhancer hs2129

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in P-body IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
RNA-binding protein MEX3A
Names
RING finger and KH domain-containing protein 4
ring finger and KH domain containing 4
ring finger and KH domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093725.2NP_001087194.1  RNA-binding protein MEX3A

    See identical proteins and their annotated locations for NP_001087194.1

    Status: VALIDATED

    Source sequence(s)
    AK125482, AL355388, AY950677, CX873216
    Consensus CDS
    CCDS53377.1
    UniProtKB/Swiss-Prot
    A1L020
    Related
    ENSP00000432845.1, ENST00000532414.3
    Conserved Domains (3) summary
    cd16518
    Location:469509
    RING-HC_MEX3; RING finger, HC subclass, found in RNA-binding proteins of the evolutionarily-conserved MEX-3 family
    cd22423
    Location:132204
    KH-I_MEX3_rpt1; first type I K homology (KH) RNA-binding domain found in the family of MEX-3 RNA-binding proteins
    cd22424
    Location:221292
    KH-I_MEX3_rpt2; second type I K homology (KH) RNA-binding domain found in the family of MEX-3 RNA-binding proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    156072013..156082465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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