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LMBRD2 LMBR1 domain containing 2 [ Homo sapiens (human) ]

Gene ID: 92255, updated on 18-Aug-2021

Summary

Official Symbol
LMBRD2provided by HGNC
Official Full Name
LMBR1 domain containing 2provided by HGNC
Primary source
HGNC:HGNC:25287
See related
Ensembl:ENSG00000164187 MIM:619490
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in brain (RPKM 10.2), thyroid (RPKM 6.1) and 25 other tissues See more
Orthologs
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Genomic context

See LMBRD2 in Genome Data Viewer
Location:
5p13.2
Exon count:
19
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (36098407..36151961, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (36098509..36151989, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene UDP glycosyltransferase family 3 member A1 Neighboring gene UDP glycosyltransferase family 3 member A2 Neighboring gene RNA, U6 small nuclear 1305, pseudogene Neighboring gene microRNA 580 Neighboring gene S-phase kinase associated protein 2 Neighboring gene NAD kinase 2, mitochondrial Neighboring gene NADK2 antisense RNA 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC125692, MGC125693, DKFZp434H2226, DKFZp686G1057

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in adrenergic receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in adrenergic receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
G-protein coupled receptor-associated protein LMBRD2
Names
LMBR1 domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007527.2NP_001007528.1  G-protein coupled receptor-associated protein LMBRD2

    See identical proteins and their annotated locations for NP_001007528.1

    Status: VALIDATED

    Source sequence(s)
    AC008942, AK091295, AL137370, BX647340, CR749399
    Consensus CDS
    CCDS34145.1
    UniProtKB/Swiss-Prot
    Q68DH5
    Related
    ENSP00000296603.4, ENST00000296603.5
    Conserved Domains (1) summary
    pfam04791
    Location:1549
    LMBR1; LMBR1-like membrane protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    36098407..36151961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011514162.2XP_011512464.1  G-protein coupled receptor-associated protein LMBRD2 isoform X1

    See identical proteins and their annotated locations for XP_011512464.1

    UniProtKB/Swiss-Prot
    Q68DH5
    Conserved Domains (1) summary
    pfam04791
    Location:1549
    LMBR1; LMBR1-like membrane protein
  2. XM_017010024.2XP_016865513.1  G-protein coupled receptor-associated protein LMBRD2 isoform X2

    Conserved Domains (1) summary
    pfam04791
    Location:28328
    LMBR1; LMBR1-like membrane protein

RNA

  1. XR_001742339.1 RNA Sequence

  2. XR_001742340.2 RNA Sequence

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