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STYXL2 serine/threonine/tyrosine interacting like 2 [ Homo sapiens (human) ]

Gene ID: 92235, updated on 10-Oct-2020

Summary

Official Symbol
STYXL2provided by HGNC
Official Full Name
serine/threonine/tyrosine interacting like 2provided by HGNC
Primary source
HGNC:HGNC:25034
See related
Ensembl:ENSG00000198842
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DUSP27
Expression
Biased expression in heart (RPKM 26.2) and prostate (RPKM 2.1) See more
Orthologs

Genomic context

See STYXL2 in Genome Data Viewer
Location:
1q24.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (167094048..167129165)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (167063314..167098402)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene maelstrom spermatogenic transposon silencer Neighboring gene RNA, 5S ribosomal pseudogene 65 Neighboring gene uncharacterized LOC105371600 Neighboring gene glycoprotein A33 Neighboring gene uncharacterized LOC105371601 Neighboring gene ribosomal protein S17 pseudogene 6

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
sarcomere IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
serine/threonine/tyrosine-interacting-like protein 2; inactive dual specificity phosphatase 27
Names
dual specificity phosphatase 27 (putative)
dual specificity phosphatase 27, atypical

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080426.3NP_001073895.1  serine/threonine/tyrosine-interacting-like protein 2

    See identical proteins and their annotated locations for NP_001073895.1

    Status: VALIDATED

    Source sequence(s)
    AL158837
    Consensus CDS
    CCDS30932.1
    UniProtKB/Swiss-Prot
    Q5VZP5
    Related
    ENSP00000354483.2, ENST00000361200.7
    Conserved Domains (1) summary
    cd00127
    Location:133275
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    167094048..167129165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510146.2XP_011508448.1  inactive dual specificity phosphatase 27 isoform X1

    Conserved Domains (1) summary
    cd00127
    Location:94236
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
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